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Article: Outbreak of Fusarium keratitis - Hong Kong experience

TitleOutbreak of Fusarium keratitis - Hong Kong experience
Authors
KeywordsContact Lens Solutions
Contact Lenses
Fusarium
Infection
Keratitis
Issue Date2007
PublisherScientific Communications International Ltd. The Journal's web site is located at http://www.scientific-com.com/AJO/
Citation
Asian Journal Of Ophthalmology, 2007, v. 9 n. 4, p. 162-166 How to Cite?
AbstractAim: To describe a regional outbreak of Fusarium keratitis among contact lens wearers in Hong Kong. Methods: In this retrospective hospital-based study, all cases of fungal keratitis among contact lens wearers receiving treatment in 1 of the 7 hospital clusters in Hong Kong (United Christian Hospital and Tseung Kwan O Hospital)from May 2005 to September 2006 were reviewed. Additional clinical information was obtained through telephone interviews conducted by the same trained interviewer. Results: Fourteen patients (16 affected eyes) were identified as contact lens wearers with culture positive Fusarium keratitis during the study period. The mean age was 31.3 years (SD, 9.4 years; range, 18 to 49 years) with female predominance (male to female ratio, 3:11). Eleven of 12 patients (92%) reported using ReNu MoistureLoc multipurpose contact lens solution prior to the onset of infection. The onset of symptoms ranged from 1 to 7 days (average, 2.5 days). Five patients (36%) were treated with topical antibiotics without the need for specific antifungal therapy. Nine patients (64%) were treated with topical antifungal therapy. No patients required therapeutic penetrating keratoplasty. Fourteen eyes (87.5%) resolved with vision 20/40 or better and no eyes had vision 20/60 or worse. No recurrence of fungal lesions was noted. Conclusions: These findings showed that the majority of the affected patients were using ReNu solution prior to infection. Early commencement of either intensive topical broad-spectrum antibiotics or antifungal treatment was associated with improved visual outcome. © 2007 Scientific Communications International Limited.
Persistent Identifierhttp://hdl.handle.net/10722/176466
ISSN
2023 SCImago Journal Rankings: 0.152
References

 

DC FieldValueLanguage
dc.contributor.authorLaw, RWKen_US
dc.contributor.authorTang, EWHen_US
dc.contributor.authorLi, RTHen_US
dc.contributor.authorLai, JSMen_US
dc.date.accessioned2012-11-26T09:11:38Z-
dc.date.available2012-11-26T09:11:38Z-
dc.date.issued2007en_US
dc.identifier.citationAsian Journal Of Ophthalmology, 2007, v. 9 n. 4, p. 162-166en_US
dc.identifier.issn1560-2133en_US
dc.identifier.urihttp://hdl.handle.net/10722/176466-
dc.description.abstractAim: To describe a regional outbreak of Fusarium keratitis among contact lens wearers in Hong Kong. Methods: In this retrospective hospital-based study, all cases of fungal keratitis among contact lens wearers receiving treatment in 1 of the 7 hospital clusters in Hong Kong (United Christian Hospital and Tseung Kwan O Hospital)from May 2005 to September 2006 were reviewed. Additional clinical information was obtained through telephone interviews conducted by the same trained interviewer. Results: Fourteen patients (16 affected eyes) were identified as contact lens wearers with culture positive Fusarium keratitis during the study period. The mean age was 31.3 years (SD, 9.4 years; range, 18 to 49 years) with female predominance (male to female ratio, 3:11). Eleven of 12 patients (92%) reported using ReNu MoistureLoc multipurpose contact lens solution prior to the onset of infection. The onset of symptoms ranged from 1 to 7 days (average, 2.5 days). Five patients (36%) were treated with topical antibiotics without the need for specific antifungal therapy. Nine patients (64%) were treated with topical antifungal therapy. No patients required therapeutic penetrating keratoplasty. Fourteen eyes (87.5%) resolved with vision 20/40 or better and no eyes had vision 20/60 or worse. No recurrence of fungal lesions was noted. Conclusions: These findings showed that the majority of the affected patients were using ReNu solution prior to infection. Early commencement of either intensive topical broad-spectrum antibiotics or antifungal treatment was associated with improved visual outcome. © 2007 Scientific Communications International Limited.en_US
dc.languageengen_US
dc.publisherScientific Communications International Ltd. The Journal's web site is located at http://www.scientific-com.com/AJO/en_US
dc.relation.ispartofAsian Journal of Ophthalmologyen_US
dc.subjectContact Lens Solutionsen_US
dc.subjectContact Lensesen_US
dc.subjectFusariumen_US
dc.subjectInfectionen_US
dc.subjectKeratitisen_US
dc.titleOutbreak of Fusarium keratitis - Hong Kong experienceen_US
dc.typeArticleen_US
dc.identifier.emailLai, JSM: laism@hku.hken_US
dc.identifier.authorityLai, JSM=rp00295en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-34548575138en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34548575138&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume9en_US
dc.identifier.issue4en_US
dc.identifier.spage162en_US
dc.identifier.epage166en_US
dc.publisher.placeHong Kongen_US
dc.identifier.scopusauthoridLaw, RWK=7201503302en_US
dc.identifier.scopusauthoridTang, EWH=7006462058en_US
dc.identifier.scopusauthoridLi, RTH=8054515600en_US
dc.identifier.scopusauthoridLai, JSM=7401939748en_US
dc.identifier.issnl1560-2133-

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