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Article: Study on treatment of iron-deficiency anemia by shengxuening
Title | Study on treatment of iron-deficiency anemia by shengxuening |
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Authors | |
Issue Date | 2004 |
Publisher | Zhongguo Zhong-Xiyi Jiehe Zazhi. The Journal's web site is located at http://zxyjh.periodicals.net.cn/ |
Citation | Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal Of Integrated Traditional And Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban, 2004, v. 24 n. 10, p. 893-896 How to Cite? |
Abstract | OBJECTIVE: To observe the therapeutic effect of shengxuening (SXN) in treating iron-deficiency anemia (IDA) and to explore its molecular mechanism on iron metabolism balance regulation. METHODS: Patients with IDA were randomly divided into the treated group and the control group, 50 in each group. They were treated with SXN (0.1 g, three times per day) and ferrous gluconate (0.1 g, three times per day) respectively, for 30 days. Levels of serum iron (Fe), total iron binding capacity (TIBC), transferrin saturation (TS), serum ferritin (SF), transferrin (Tf), soluble transferrin receptor (sTfR) and blood routine test, as well as scoring of TCM qi-blood deficiency Syndrome were conducted before and after treatment. RESULTS: The total effective rate in the treated group reached 92%, it was shown that SXN could improve the iron metabolism, increase levels of Fe, TS, SF and reduce levels of TIBC, Tf, sTfR, it has obvious effect in promoting erythrocyte generation and could promote formation of leucocytes and platelets. The total effective rate in the control group was 32%, which was significantly lower than that in the treated group (P < 0.01). CONCLUSION: The effect of SXN in treating IDA and qi-blood deficiency Syndrome is evident, it could improve the iron metabolism, increase levels of Fe, TS, SF and lower levels of TIBC, Tf, sTfR. |
Persistent Identifier | http://hdl.handle.net/10722/179422 |
ISSN | 2019 SCImago Journal Rankings: 0.132 |
DC Field | Value | Language |
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dc.contributor.author | Ke, YF | en_US |
dc.contributor.author | Wei, KM | en_US |
dc.contributor.author | Zheng, JX | en_US |
dc.contributor.author | Pu, J | en_US |
dc.contributor.author | Zhu, Y | en_US |
dc.contributor.author | Liang, W | en_US |
dc.date.accessioned | 2012-12-19T09:56:21Z | - |
dc.date.available | 2012-12-19T09:56:21Z | - |
dc.date.issued | 2004 | en_US |
dc.identifier.citation | Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal Of Integrated Traditional And Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban, 2004, v. 24 n. 10, p. 893-896 | en_US |
dc.identifier.issn | 1003-5370 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/179422 | - |
dc.description.abstract | OBJECTIVE: To observe the therapeutic effect of shengxuening (SXN) in treating iron-deficiency anemia (IDA) and to explore its molecular mechanism on iron metabolism balance regulation. METHODS: Patients with IDA were randomly divided into the treated group and the control group, 50 in each group. They were treated with SXN (0.1 g, three times per day) and ferrous gluconate (0.1 g, three times per day) respectively, for 30 days. Levels of serum iron (Fe), total iron binding capacity (TIBC), transferrin saturation (TS), serum ferritin (SF), transferrin (Tf), soluble transferrin receptor (sTfR) and blood routine test, as well as scoring of TCM qi-blood deficiency Syndrome were conducted before and after treatment. RESULTS: The total effective rate in the treated group reached 92%, it was shown that SXN could improve the iron metabolism, increase levels of Fe, TS, SF and reduce levels of TIBC, Tf, sTfR, it has obvious effect in promoting erythrocyte generation and could promote formation of leucocytes and platelets. The total effective rate in the control group was 32%, which was significantly lower than that in the treated group (P < 0.01). CONCLUSION: The effect of SXN in treating IDA and qi-blood deficiency Syndrome is evident, it could improve the iron metabolism, increase levels of Fe, TS, SF and lower levels of TIBC, Tf, sTfR. | en_US |
dc.language | eng | en_US |
dc.publisher | Zhongguo Zhong-Xiyi Jiehe Zazhi. The Journal's web site is located at http://zxyjh.periodicals.net.cn/ | en_US |
dc.relation.ispartof | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban | en_US |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Anemia, Iron-Deficiency - Blood - Drug Therapy | en_US |
dc.subject.mesh | Child | en_US |
dc.subject.mesh | Drugs, Chinese Herbal - Therapeutic Use | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Ferritins - Blood | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Iron - Blood | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Phytotherapy | en_US |
dc.subject.mesh | Receptors, Transferrin - Blood | en_US |
dc.title | Study on treatment of iron-deficiency anemia by shengxuening | en_US |
dc.type | Article | en_US |
dc.identifier.email | Ke, YF: keyoufu@hkucc.hku.hk | en_US |
dc.identifier.authority | Ke, YF=rp01340 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 15553821 | - |
dc.identifier.scopus | eid_2-s2.0-16644373094 | en_US |
dc.identifier.volume | 24 | en_US |
dc.identifier.issue | 10 | en_US |
dc.identifier.spage | 893 | en_US |
dc.identifier.epage | 896 | en_US |
dc.publisher.place | China | en_US |
dc.identifier.scopusauthorid | Ke, YF=8295702600 | en_US |
dc.identifier.scopusauthorid | Wei, KM=36723563800 | en_US |
dc.identifier.scopusauthorid | Zheng, JX=8295702200 | en_US |
dc.identifier.scopusauthorid | Pu, J=8295702300 | en_US |
dc.identifier.scopusauthorid | Zhu, Y=35779652400 | en_US |
dc.identifier.scopusauthorid | Liang, W=8295702500 | en_US |
dc.identifier.issnl | 1003-5370 | - |