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- Publisher Website: 10.1093/oxfordjournals.rpd.a033024
- Scopus: eid_2-s2.0-0034026871
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Conference Paper: Views on issues in radiation biodosimetry based on chromosome translocations measured by FISH
Title | Views on issues in radiation biodosimetry based on chromosome translocations measured by FISH |
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Other Titles | Our views on issues in radiation biodosimetry based on chromosome translocations measured by FISH |
Authors | |
Issue Date | 2000 |
Publisher | Oxford University Press. The Journal's web site is located at http://rpd.oxfordjournals.org/ |
Citation | Radiation Protection Dosimetry, 2000, v. 88 n. 1, p. 77-86 How to Cite? |
Abstract | A biomarker for retrospective biodosimetry for radiation exposure and human health risk assessment would be most useful if it employed an endpoint that is highly quantitative, is stable over time, and is relevant to human health risk. The frequency of chromosome translocations in individuals exposed to low to medium doses of whole-body radiation serves these goals. Recent advances in chromosome painting using fluorescence in situ hybridisation (FISH) facilitate fast and reliable measurement of chromosome translocations, a kind of DNA damage linked to both prior clastogenic exposure and to human health risk. Here, results from this laboratory on issues of FISH-based radiation biodosimetry are discussed. |
Persistent Identifier | http://hdl.handle.net/10722/179618 |
ISSN | 2023 Impact Factor: 0.8 2023 SCImago Journal Rankings: 0.264 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Lucas, JN | en_US |
dc.contributor.author | Deng, W | en_US |
dc.date.accessioned | 2012-12-19T10:01:09Z | - |
dc.date.available | 2012-12-19T10:01:09Z | - |
dc.date.issued | 2000 | en_US |
dc.identifier.citation | Radiation Protection Dosimetry, 2000, v. 88 n. 1, p. 77-86 | en_US |
dc.identifier.issn | 0144-8420 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/179618 | - |
dc.description.abstract | A biomarker for retrospective biodosimetry for radiation exposure and human health risk assessment would be most useful if it employed an endpoint that is highly quantitative, is stable over time, and is relevant to human health risk. The frequency of chromosome translocations in individuals exposed to low to medium doses of whole-body radiation serves these goals. Recent advances in chromosome painting using fluorescence in situ hybridisation (FISH) facilitate fast and reliable measurement of chromosome translocations, a kind of DNA damage linked to both prior clastogenic exposure and to human health risk. Here, results from this laboratory on issues of FISH-based radiation biodosimetry are discussed. | en_US |
dc.language | eng | en_US |
dc.publisher | Oxford University Press. The Journal's web site is located at http://rpd.oxfordjournals.org/ | en_US |
dc.relation.ispartof | Radiation Protection Dosimetry | en_US |
dc.title | Views on issues in radiation biodosimetry based on chromosome translocations measured by FISH | en_US |
dc.title.alternative | Our views on issues in radiation biodosimetry based on chromosome translocations measured by FISH | - |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Deng, W: wdeng@hkucc.hku.hk | en_US |
dc.identifier.authority | Deng, W=rp01640 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1093/oxfordjournals.rpd.a033024 | - |
dc.identifier.scopus | eid_2-s2.0-0034026871 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0034026871&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 88 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.spage | 77 | en_US |
dc.identifier.epage | 86 | en_US |
dc.identifier.isi | WOS:000087035500011 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Lucas, JN=7402441937 | en_US |
dc.identifier.scopusauthorid | Deng, W=7202223673 | en_US |
dc.customcontrol.immutable | sml 160531 amended | - |
dc.identifier.issnl | 0144-8420 | - |