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Article: Increase in severity of graft versus host disease by cytomegalovirus

TitleIncrease in severity of graft versus host disease by cytomegalovirus
Authors
Mccarthy, ALMalik Peiris, JSTaylor, CEGreen, MASviland, LPearson, ADJMalcolm, AJ
Issue Date1992
PublisherB M J Publishing Group. The Journal's web site is located at http://jcp.bmjjournals.com/
Citation
Journal Of Clinical Pathology, 1992, v. 45 n. 6, p. 542-544 How to Cite?
DOI: http://dx.doi.org/10.1136/jcp.45.6.542
AbstractAn allogeneic transplant recipient developed severe graft versus host disease (GvHD) 48 days after transplantation that was concomitant with a cytomegalovirus (CMV) viraemia, from which she subsequently died. CMV infection was detected in blood by the polymerase chain reaction and later in tissue by immunohistochemical techniques. CMV should be considered in patients in whom GvHD does not respond to appropriate treatment, and this case suggests that herpes viruses may increase the severity of GvHD by synergistically enhancing the graft versus host reaction.
Persistent Identifierhttp://hdl.handle.net/10722/179745
ISSN
0021-9746
2023 Impact Factor: 2.5
2023 SCImago Journal Rankings: 0.934
ISI Accession Number ID
WOS:A1992HY09100024

 

DC FieldValueLanguage
dc.contributor.authorMccarthy, ALen_US
dc.contributor.authorMalik Peiris, JSen_US
dc.contributor.authorTaylor, CEen_US
dc.contributor.authorGreen, MAen_US
dc.contributor.authorSviland, Len_US
dc.contributor.authorPearson, ADJen_US
dc.contributor.authorMalcolm, AJen_US
dc.date.accessioned2012-12-19T10:04:15Z-
dc.date.available2012-12-19T10:04:15Z-
dc.date.issued1992en_US
dc.identifier.citationJournal Of Clinical Pathology, 1992, v. 45 n. 6, p. 542-544en_US
dc.identifier.issn0021-9746en_US
dc.identifier.urihttp://hdl.handle.net/10722/179745-
dc.description.abstractAn allogeneic transplant recipient developed severe graft versus host disease (GvHD) 48 days after transplantation that was concomitant with a cytomegalovirus (CMV) viraemia, from which she subsequently died. CMV infection was detected in blood by the polymerase chain reaction and later in tissue by immunohistochemical techniques. CMV should be considered in patients in whom GvHD does not respond to appropriate treatment, and this case suggests that herpes viruses may increase the severity of GvHD by synergistically enhancing the graft versus host reaction.en_US
dc.languageengen_US
dc.publisherB M J Publishing Group. The Journal's web site is located at http://jcp.bmjjournals.com/en_US
dc.relation.ispartofJournal of Clinical Pathologyen_US
dc.subject.meshAdulten_US
dc.subject.meshBone Marrow Transplantationen_US
dc.subject.meshCytomegalovirus Infections - Complications - Diagnosisen_US
dc.subject.meshFemaleen_US
dc.subject.meshGraft Vs Host Disease - Etiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshPolymerase Chain Reactionen_US
dc.subject.meshViremia - Complicationsen_US
dc.titleIncrease in severity of graft versus host disease by cytomegalovirusen_US
dc.typeArticleen_US
dc.identifier.emailMalik Peiris, JS: malik@hkucc.hku.hken_US
dc.identifier.authorityMalik Peiris, JS=rp00410en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1136/jcp.45.6.542-
dc.identifier.pmid1320637-
dc.identifier.scopuseid_2-s2.0-0026773543en_US
dc.identifier.volume45en_US
dc.identifier.issue6en_US
dc.identifier.spage542en_US
dc.identifier.epage544en_US
dc.identifier.isiWOS:A1992HY09100024-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridMcCarthy, AL=7102038738en_US
dc.identifier.scopusauthoridMalik Peiris, JS=7005486823en_US
dc.identifier.scopusauthoridTaylor, CE=7404822545en_US
dc.identifier.scopusauthoridGreen, MA=16143678900en_US
dc.identifier.scopusauthoridSviland, L=7003823044en_US
dc.identifier.scopusauthoridPearson, ADJ=7401994312en_US
dc.identifier.scopusauthoridMalcolm, AJ=7103265161en_US
dc.identifier.issnl0021-9746-

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