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Article: Fibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine

TitleFibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine
Authors
Sze, HYeung, MW
KeywordsAirway obstruction
Chemotherapy, adjuvant
Fibromatosis, aggressive
Head and neck neoplasms
Issue Date2009
PublisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk
Citation
Hong Kong Medical Journal, 2009, v. 15 n. 3, p. 221-223 How to Cite?
AbstractFibromatosis is a rare disease with benign histology. Its infiltrative growth pattern may prevent complete resection. We report a case of a 40-year-old woman with fibromatosis of the neck requiring an emergency operation for acute upper airway obstruction. Gross residual tumour was left behind but excellent tumour shrinkage was achieved by using weekly low-dose methotrexate and vinblastine. Despite the use of newer agents such as imatinib, cytotoxic chemotherapy remains an efficacious treatment for inoperable fibromatosis.
Persistent Identifierhttp://hdl.handle.net/10722/180450
ISSN
1024-2708
2021 Impact Factor: 1.256
2020 SCImago Journal Rankings: 0.357
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorSze, Hen_US
dc.contributor.authorYeung, MWen_US
dc.date.accessioned2013-01-28T01:38:13Z-
dc.date.available2013-01-28T01:38:13Z-
dc.date.issued2009en_US
dc.identifier.citationHong Kong Medical Journal, 2009, v. 15 n. 3, p. 221-223en_US
dc.identifier.issn1024-2708en_US
dc.identifier.urihttp://hdl.handle.net/10722/180450-
dc.description.abstractFibromatosis is a rare disease with benign histology. Its infiltrative growth pattern may prevent complete resection. We report a case of a 40-year-old woman with fibromatosis of the neck requiring an emergency operation for acute upper airway obstruction. Gross residual tumour was left behind but excellent tumour shrinkage was achieved by using weekly low-dose methotrexate and vinblastine. Despite the use of newer agents such as imatinib, cytotoxic chemotherapy remains an efficacious treatment for inoperable fibromatosis.en_US
dc.languageengen_US
dc.publisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hken_US
dc.relation.ispartofHong Kong Medical Journalen_US
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectAirway obstruction-
dc.subjectChemotherapy, adjuvant-
dc.subjectFibromatosis, aggressive-
dc.subjectHead and neck neoplasms-
dc.subject.meshAdulten_US
dc.subject.meshAirway Obstruction - Etiologyen_US
dc.subject.meshAntimetabolites, Antineoplastic - Administration & Dosageen_US
dc.subject.meshAntineoplastic Agents, Phytogenic - Administration & Dosageen_US
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols - Therapeutic Useen_US
dc.subject.meshFemaleen_US
dc.subject.meshFibroma - Complications - Drug Therapy - Radiographyen_US
dc.subject.meshHead And Neck Neoplasms - Complications - Drug Therapy - Radiographyen_US
dc.subject.meshHumansen_US
dc.subject.meshMethotrexate - Administration & Dosageen_US
dc.subject.meshVinblastine - Administration & Dosageen_US
dc.titleFibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastineen_US
dc.typeArticleen_US
dc.identifier.emailSze, H: henrysze@graduate.hku.hken_US
dc.identifier.authoritySze, H=rp01697en_US
dc.description.naturepublished_or_final_versionen_US
dc.identifier.pmid19494380-
dc.identifier.scopuseid_2-s2.0-67650501029en_US
dc.identifier.hkuros219067-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67650501029&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume15en_US
dc.identifier.issue3en_US
dc.identifier.spage221en_US
dc.identifier.epage223en_US
dc.publisher.placeHong Kongen_US
dc.identifier.scopusauthoridSze, H=23490726900en_US
dc.identifier.scopusauthoridYeung, MW=7101861680en_US
dc.identifier.issnl1024-2708-

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