The role of Eigen-matrix translation in classification of biological datasets

Abstract

Driven by the challenge of integrating large amount of experimental data obtained from biological research, computational biology and bioinformatics are growing rapidly. Machine learning methods, especially kernel methods with Support Vector Machines (SVMs) are very popular tools. In the perspective of kernel matrix, a technique namely Eigen-matrix translation has been introduced for protein data classification. The Eigen-matrix translation strategy owns a lot of nice properties while the nature of which needs further exploration. We propose that its importance lies in the dimension reduction of predictor attributes within the data set. This can therefore serve as a novel perspective for future research in dimension reduction problems. © 2012 IEEE.