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- Publisher Website: 10.1111/j.1479-828X.1983.tb00568.x
- Scopus: eid_2-s2.0-0020519834
- PMID: 6580885
- WOS: WOS:A1983RH65000009
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Article: Hyperprolactinaemic amenorrhoea in Hong Kong
Title | Hyperprolactinaemic amenorrhoea in Hong Kong |
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Authors | |
Issue Date | 1983 |
Publisher | Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANZJOG |
Citation | Australian And New Zealand Journal Of Obstetrics And Gynaecology, 1983, v. 23 n. 3, p. 165-169 How to Cite? |
Abstract | In a retrospective study of 595 patients attending the Menstrual Disorder Clinic from January, 1978 to December, 1981, 92 patients (15.5%) had raised serum prolactin (PRL) levels (>25 ng/ml) on 2 or more separate occasions with a mean (±S.E.M.) value of 67.1 ± 2.5 ng/ml. Galactorrhoea was found in 27.2% of the hyperprolactinaemic patients. Primary amenorrhoea was observed in 1 patient (1.1%) with serum PRL level of 68 ng/ml. Secondary amenorrhoea of longer than 6 months' duration occurred in 61 patients (66.3%) with mean PRL level 84.2 ± 3.3 ng/ml. The 30 patients (32.6%) with irregular menstruation had a mean PRL level of 47.2 ± 3.3 ng/ml. Investigations revealed that 43 patients (46.7%) had idiopathic hyperprolactinaemia, 14 patients (15.4%) had drug induced hyperprolactinaemia and 1 patient (1.1%) had hypothyroidism; 18 patients (19.5%) had suspected pituitary microadenoma and 16 patients (17.2%) had abnormal radiographic findings. Bromocriptine treatment was given to 38 patients, 13 with abnormal tomographic findings (mean serum PRL > 100 ng/ml); 18 with suspected pituitary microadenoma (mean serum PRL 94 ± 2.7 ng/ml) and 7 with idiopathic hyperprolactinaemia (mean serum PRL 65 ± 4.7 ng/ml). All patients (38/38) responded to treatment with restoration of menstruation and cessation of galactorrhoea with 1 to 3 months. Mean PRL level was 21.6 ± 5.2 ng/ml at the time of response. Thirteen patients subsequently became pregnant and all delivered healthy babies. |
Persistent Identifier | http://hdl.handle.net/10722/184148 |
ISSN | 2023 Impact Factor: 1.4 2023 SCImago Journal Rankings: 0.630 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Tang, LCH | en_US |
dc.contributor.author | Sung, ML | en_US |
dc.contributor.author | Ma, HK | en_US |
dc.date.accessioned | 2013-06-25T03:00:44Z | - |
dc.date.available | 2013-06-25T03:00:44Z | - |
dc.date.issued | 1983 | en_US |
dc.identifier.citation | Australian And New Zealand Journal Of Obstetrics And Gynaecology, 1983, v. 23 n. 3, p. 165-169 | en_US |
dc.identifier.issn | 0004-8666 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/184148 | - |
dc.description.abstract | In a retrospective study of 595 patients attending the Menstrual Disorder Clinic from January, 1978 to December, 1981, 92 patients (15.5%) had raised serum prolactin (PRL) levels (>25 ng/ml) on 2 or more separate occasions with a mean (±S.E.M.) value of 67.1 ± 2.5 ng/ml. Galactorrhoea was found in 27.2% of the hyperprolactinaemic patients. Primary amenorrhoea was observed in 1 patient (1.1%) with serum PRL level of 68 ng/ml. Secondary amenorrhoea of longer than 6 months' duration occurred in 61 patients (66.3%) with mean PRL level 84.2 ± 3.3 ng/ml. The 30 patients (32.6%) with irregular menstruation had a mean PRL level of 47.2 ± 3.3 ng/ml. Investigations revealed that 43 patients (46.7%) had idiopathic hyperprolactinaemia, 14 patients (15.4%) had drug induced hyperprolactinaemia and 1 patient (1.1%) had hypothyroidism; 18 patients (19.5%) had suspected pituitary microadenoma and 16 patients (17.2%) had abnormal radiographic findings. Bromocriptine treatment was given to 38 patients, 13 with abnormal tomographic findings (mean serum PRL > 100 ng/ml); 18 with suspected pituitary microadenoma (mean serum PRL 94 ± 2.7 ng/ml) and 7 with idiopathic hyperprolactinaemia (mean serum PRL 65 ± 4.7 ng/ml). All patients (38/38) responded to treatment with restoration of menstruation and cessation of galactorrhoea with 1 to 3 months. Mean PRL level was 21.6 ± 5.2 ng/ml at the time of response. Thirteen patients subsequently became pregnant and all delivered healthy babies. | en_US |
dc.language | eng | en_US |
dc.publisher | Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANZJOG | en_US |
dc.relation.ispartof | Australian and New Zealand Journal of Obstetrics and Gynaecology | en_US |
dc.subject.mesh | Adenoma - Complications | en_US |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Amenorrhea - Drug Therapy - Etiology | en_US |
dc.subject.mesh | Bromocriptine - Therapeutic Use | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Galactorrhea - Drug Therapy - Etiology | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Hypothyroidism - Complications | en_US |
dc.subject.mesh | Infertility, Female - Drug Therapy - Etiology | en_US |
dc.subject.mesh | Lactation Disorders - Drug Therapy | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Pituitary Neoplasms - Complications | en_US |
dc.subject.mesh | Pregnancy | en_US |
dc.subject.mesh | Prolactin - Blood | en_US |
dc.title | Hyperprolactinaemic amenorrhoea in Hong Kong | en_US |
dc.type | Article | en_US |
dc.identifier.email | Tang, LCH: lchtang@hku.hk | en_US |
dc.identifier.authority | Tang, LCH=rp01756 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1111/j.1479-828X.1983.tb00568.x | - |
dc.identifier.pmid | 6580885 | en_US |
dc.identifier.scopus | eid_2-s2.0-0020519834 | en_US |
dc.identifier.volume | 23 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.spage | 165 | en_US |
dc.identifier.epage | 169 | en_US |
dc.identifier.isi | WOS:A1983RH65000009 | - |
dc.publisher.place | Australia | en_US |
dc.identifier.scopusauthorid | Tang, LCH=7402081111 | en_US |
dc.identifier.scopusauthorid | Sung, ML=36874592900 | en_US |
dc.identifier.scopusauthorid | Ma, HK=7403095603 | en_US |
dc.identifier.issnl | 0004-8666 | - |