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- Scopus: eid_2-s2.0-0021818704
- PMID: 4007185
- WOS: WOS:A1985AMH8500018
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Article: Clomiphene citrate does not improve spermatozoal fertilizing capacity in idiopathic oligospermia
Title | Clomiphene citrate does not improve spermatozoal fertilizing capacity in idiopathic oligospermia |
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Authors | |
Issue Date | 1985 |
Publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/fertnstert |
Citation | Fertility And Sterility, 1985, v. 44 n. 1, p. 102-105 How to Cite? |
Abstract | Clomiphene citrate (CC) was given to 24 men with idiopathic oligospermia at a daily dose of 25 mg (10 subjects) or 50 mg (14 subjects). Sperm concentration increased slightly after CC treatment in both groups. Sperm motility and morphology remained unchanged. Spermatozoal fertilizing capacity as assessed by the zona-free hamster ova penetration test showed no significant change throughout the treatment period. Two pregnancies occurred in the partners of the subjects treated with 50 mg CC/day, but none occurred in the other group. We conclude that oral administration of CC does not improve fertilizing capacity of sperm as measured by the zona-free hamster ova penetration test in idiopathic oligospermia. |
Persistent Identifier | http://hdl.handle.net/10722/184166 |
ISSN | 2023 Impact Factor: 6.6 2023 SCImago Journal Rankings: 1.858 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Wang, C | en_US |
dc.contributor.author | Chan, SYW | en_US |
dc.contributor.author | Tang, LCH | en_US |
dc.contributor.author | Yeung, KK | en_US |
dc.date.accessioned | 2013-06-25T03:00:56Z | - |
dc.date.available | 2013-06-25T03:00:56Z | - |
dc.date.issued | 1985 | en_US |
dc.identifier.citation | Fertility And Sterility, 1985, v. 44 n. 1, p. 102-105 | en_US |
dc.identifier.issn | 0015-0282 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/184166 | - |
dc.description.abstract | Clomiphene citrate (CC) was given to 24 men with idiopathic oligospermia at a daily dose of 25 mg (10 subjects) or 50 mg (14 subjects). Sperm concentration increased slightly after CC treatment in both groups. Sperm motility and morphology remained unchanged. Spermatozoal fertilizing capacity as assessed by the zona-free hamster ova penetration test showed no significant change throughout the treatment period. Two pregnancies occurred in the partners of the subjects treated with 50 mg CC/day, but none occurred in the other group. We conclude that oral administration of CC does not improve fertilizing capacity of sperm as measured by the zona-free hamster ova penetration test in idiopathic oligospermia. | en_US |
dc.language | eng | en_US |
dc.publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/fertnstert | en_US |
dc.relation.ispartof | Fertility and Sterility | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Clomiphene - Therapeutic Use | en_US |
dc.subject.mesh | Cricetinae | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Oligospermia - Drug Therapy - Physiopathology | en_US |
dc.subject.mesh | Sperm Count | en_US |
dc.subject.mesh | Sperm Motility - Drug Effects | en_US |
dc.subject.mesh | Sperm-Ovum Interactions - Drug Effects | en_US |
dc.subject.mesh | Time Factors | en_US |
dc.title | Clomiphene citrate does not improve spermatozoal fertilizing capacity in idiopathic oligospermia | en_US |
dc.type | Article | en_US |
dc.identifier.email | Tang, LCH: lchtang@hku.hk | en_US |
dc.identifier.authority | Tang, LCH=rp01756 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 4007185 | - |
dc.identifier.scopus | eid_2-s2.0-0021818704 | en_US |
dc.identifier.volume | 44 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.spage | 102 | en_US |
dc.identifier.epage | 105 | en_US |
dc.identifier.isi | WOS:A1985AMH8500018 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Wang, C=7501631357 | en_US |
dc.identifier.scopusauthorid | Chan, SYW=7404255960 | en_US |
dc.identifier.scopusauthorid | Tang, LCH=7402081111 | en_US |
dc.identifier.scopusauthorid | Yeung, KK=7202425010 | en_US |
dc.identifier.issnl | 0015-0282 | - |