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Conference Paper: Effect of crystallinity on electrostatic charging in DPI formulations

TitleEffect of crystallinity on electrostatic charging in DPI formulations
Authors
Wong, JKwok, PCLFathi, ADehghani, FChan, HK
Issue Date2013
PublisherInhalation Asia 2013. The Conference Abstracts' web site is located at http://www.inhalationasia.org/images/IA2013-book.pdf
Citation
The 2013 Conference of Inhalation ASIA, Hong Kong, 26-28 June 2013. In Conference Abstracts Book, 2013, p. 78, abstract no. 13PS41 How to Cite?
AbstractIntroduction: Many physicochemical, mechanical and environmental factors can influence charging of dry powder inhaler (DPI) formulations - crystallinity is one of these factors. Due to differences in crystal packing and surface energies, there may be differences in charge transfer behaviours between amorphous and crystalline materials. Although the effect of crystallinity on electrostatic charging in DPI formulations has been investigated previously by other researchers, the reported data were inconclusive since the samples not only differed in crystallinity, but also in particle morphology and size distributions. Therefore, these variables are controlled in the present study to determine the role of crystallinity in electrostatic charging of DPI formulations. The objective of this study was to characterize inherent charges generated by amorphous and crystalline micron-sized salbutamol sulfate (SS) powders .....
DescriptionPoster Presentation: no. 13PS41
Persistent Identifierhttp://hdl.handle.net/10722/190142

 

DC FieldValueLanguage
dc.contributor.authorWong, Jen_US
dc.contributor.authorKwok, PCLen_US
dc.contributor.authorFathi, Aen_US
dc.contributor.authorDehghani, Fen_US
dc.contributor.authorChan, HKen_US
dc.date.accessioned2013-09-17T15:12:58Z-
dc.date.available2013-09-17T15:12:58Z-
dc.date.issued2013en_US
dc.identifier.citationThe 2013 Conference of Inhalation ASIA, Hong Kong, 26-28 June 2013. In Conference Abstracts Book, 2013, p. 78, abstract no. 13PS41en_US
dc.identifier.urihttp://hdl.handle.net/10722/190142-
dc.descriptionPoster Presentation: no. 13PS41-
dc.description.abstractIntroduction: Many physicochemical, mechanical and environmental factors can influence charging of dry powder inhaler (DPI) formulations - crystallinity is one of these factors. Due to differences in crystal packing and surface energies, there may be differences in charge transfer behaviours between amorphous and crystalline materials. Although the effect of crystallinity on electrostatic charging in DPI formulations has been investigated previously by other researchers, the reported data were inconclusive since the samples not only differed in crystallinity, but also in particle morphology and size distributions. Therefore, these variables are controlled in the present study to determine the role of crystallinity in electrostatic charging of DPI formulations. The objective of this study was to characterize inherent charges generated by amorphous and crystalline micron-sized salbutamol sulfate (SS) powders .....-
dc.languageengen_US
dc.publisherInhalation Asia 2013. The Conference Abstracts' web site is located at http://www.inhalationasia.org/images/IA2013-book.pdf-
dc.relation.ispartofInhalation Asia Conferenceen_US
dc.rights2013@Inhalation Asia-
dc.titleEffect of crystallinity on electrostatic charging in DPI formulationsen_US
dc.typeConference_Paperen_US
dc.identifier.emailKwok, PCL: pclkwok@hku.hken_US
dc.identifier.emailChan, HK: kimchan1@hku.hken_US
dc.identifier.authorityKwok, PCL=rp01540en_US
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros222471en_US
dc.identifier.spage78, abstract no. 13PS41-
dc.identifier.epage78, abstract no. 13PS41-
dc.publisher.placeHong Kong-

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