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Conference Paper: Design of dry powder formulations of pH responsive peptide/plasmid DNA complexes for pulmonary delivery

TitleDesign of dry powder formulations of pH responsive peptide/plasmid DNA complexes for pulmonary delivery
Authors
Liang, WKwok, PCLChow, YTTang, PMason, AJChan, HKLam, JKW
Issue Date2013
PublisherInhalation Asia 2013. The Conference abstracts' web site is located at http://inhalationasia.org/index.php/poster-presentations/175-13ps50-wanling-liang
Citation
The 2013 Conference of Inhalation ASIA, Hong Kong, 26-28 June 2013, abstract no. 13PS50 How to Cite?
AbstractRespiratory diseases are substantial public health problems around the world. Recently, nucleic acid was developed as a potential therapeutic strategy to tackle a series of lung diseases. Delivery still poses one of the major challenges for their clinical application. pH responsive peptides containing either histidine or derivatives of 2,3-diaminopropionic acid (Dap) can mediate effective DNA transfection in lung epithelial cells with the latter remaining effective even in the presence of lung surfactant containing bronchoalveolar fluid (BALF), which make them promising vectors for delivering therapeutic nucleic acid to the airways .....
DescriptionPoster Presentation: no. 13PS50
Persistent Identifierhttp://hdl.handle.net/10722/190144

 

DC FieldValueLanguage
dc.contributor.authorLiang, Wen_US
dc.contributor.authorKwok, PCLen_US
dc.contributor.authorChow, YTen_US
dc.contributor.authorTang, Pen_US
dc.contributor.authorMason, AJen_US
dc.contributor.authorChan, HKen_US
dc.contributor.authorLam, JKWen_US
dc.date.accessioned2013-09-17T15:13:01Z-
dc.date.available2013-09-17T15:13:01Z-
dc.date.issued2013en_US
dc.identifier.citationThe 2013 Conference of Inhalation ASIA, Hong Kong, 26-28 June 2013, abstract no. 13PS50en_US
dc.identifier.urihttp://hdl.handle.net/10722/190144-
dc.descriptionPoster Presentation: no. 13PS50-
dc.description.abstractRespiratory diseases are substantial public health problems around the world. Recently, nucleic acid was developed as a potential therapeutic strategy to tackle a series of lung diseases. Delivery still poses one of the major challenges for their clinical application. pH responsive peptides containing either histidine or derivatives of 2,3-diaminopropionic acid (Dap) can mediate effective DNA transfection in lung epithelial cells with the latter remaining effective even in the presence of lung surfactant containing bronchoalveolar fluid (BALF), which make them promising vectors for delivering therapeutic nucleic acid to the airways .....-
dc.languageengen_US
dc.publisherInhalation Asia 2013. The Conference abstracts' web site is located at http://inhalationasia.org/index.php/poster-presentations/175-13ps50-wanling-liang-
dc.relation.ispartofInhalation Asia Conferenceen_US
dc.rights2013@Inhalation Asia-
dc.titleDesign of dry powder formulations of pH responsive peptide/plasmid DNA complexes for pulmonary deliveryen_US
dc.typeConference_Paperen_US
dc.identifier.emailKwok, PCL: pclkwok@hku.hken_US
dc.identifier.emailChan, HK: kimchan1@hku.hken_US
dc.identifier.emailLam, JKW: jkwlam@hku.hken_US
dc.identifier.authorityKwok, PCL=rp01540en_US
dc.identifier.authorityLam, JKW=rp01346en_US
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros222476en_US
dc.identifier.spageabstract no. 13PS50-
dc.identifier.epageabstract no. 13PS50-
dc.publisher.placeHong Kong-

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