File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1097/01.sla.0000262785.46403.9b
- Scopus: eid_2-s2.0-34347335723
- PMID: 17592299
- WOS: WOS:000247672300018
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Staging systems for papillary thyroid carcinoma: A study of 2 tertiary referral centers
Title | Staging systems for papillary thyroid carcinoma: A study of 2 tertiary referral centers |
---|---|
Authors | |
Issue Date | 2007 |
Publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://www.annalsofsurgery.com |
Citation | Annals of Surgery, 2007, v. 246 n. 1, p. 114-121 How to Cite? |
Abstract | OBJECTIVE: To find out the most applicable and consistent staging system for papillary thyroid carcinoma (PTC) available in the literature. BACKGROUND: The commonly used staging systems for PTC have predicted cancer-specific survival (CSS) well. However, their applicability and generalizability have not yet been evaluated in different clinical settings. METHODS: A MEDLINE search from 1965 to 2005 was carried out to identify different staging systems available in the literature and 9 systems were applicable to 1634 PTC patients within 2 tertiary-referral centers. The CSS of each staging system within individual centers were calculated using Kaplan-Meier method and the CSS of each tumor stage in one individual center was compared with that of the other by log-rank test. In addition, within each center, the predictability of each staging system relative to the others was ranked based on the proportion of variation explained (PVE) value. RESULTS: Clinicopathologic features, treatment received, and tumor stages were significantly different between the 2 centers. There were also significant differences in CSS within at least one tumor stage between the 2 centers in 8 of the 9 staging systems. The TNM was a highly predictive and consistent staging system within the 2 centers. Although the absolute PVE values differed between the 2 centers, the relative ranking of the 9 staging systems within each center correlated significantly to each other (P < 0.05). CONCLUSIONS: Despite referral, treatment, and data collection biases inherent within each center, the TNM system remained to be the most applicable and consistent staging system for PTC in 2 centers managing the same population group. |
Persistent Identifier | http://hdl.handle.net/10722/192062 |
ISSN | 2023 Impact Factor: 7.5 2023 SCImago Journal Rankings: 2.729 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lang, BHH | - |
dc.contributor.author | Chow, SM | - |
dc.contributor.author | Lo, CY | - |
dc.contributor.author | Law, SCK | - |
dc.contributor.author | Lam, KY | - |
dc.date.accessioned | 2013-10-16T09:27:18Z | - |
dc.date.available | 2013-10-16T09:27:18Z | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | Annals of Surgery, 2007, v. 246 n. 1, p. 114-121 | - |
dc.identifier.issn | 0003-4932 | - |
dc.identifier.uri | http://hdl.handle.net/10722/192062 | - |
dc.description.abstract | OBJECTIVE: To find out the most applicable and consistent staging system for papillary thyroid carcinoma (PTC) available in the literature. BACKGROUND: The commonly used staging systems for PTC have predicted cancer-specific survival (CSS) well. However, their applicability and generalizability have not yet been evaluated in different clinical settings. METHODS: A MEDLINE search from 1965 to 2005 was carried out to identify different staging systems available in the literature and 9 systems were applicable to 1634 PTC patients within 2 tertiary-referral centers. The CSS of each staging system within individual centers were calculated using Kaplan-Meier method and the CSS of each tumor stage in one individual center was compared with that of the other by log-rank test. In addition, within each center, the predictability of each staging system relative to the others was ranked based on the proportion of variation explained (PVE) value. RESULTS: Clinicopathologic features, treatment received, and tumor stages were significantly different between the 2 centers. There were also significant differences in CSS within at least one tumor stage between the 2 centers in 8 of the 9 staging systems. The TNM was a highly predictive and consistent staging system within the 2 centers. Although the absolute PVE values differed between the 2 centers, the relative ranking of the 9 staging systems within each center correlated significantly to each other (P < 0.05). CONCLUSIONS: Despite referral, treatment, and data collection biases inherent within each center, the TNM system remained to be the most applicable and consistent staging system for PTC in 2 centers managing the same population group. | - |
dc.language | eng | - |
dc.publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://www.annalsofsurgery.com | - |
dc.relation.ispartof | Annals of Surgery | - |
dc.rights | This is a non-final version of an article published in final form in Annals of Surgery, 2007, v. 246 n. 1, p. 114-121 | - |
dc.subject.mesh | Carcinoma, Papillary - mortality - pathology | - |
dc.subject.mesh | Neoplasm Staging - instrumentation | - |
dc.subject.mesh | Referral and Consultation | - |
dc.subject.mesh | Reproducibility of Results | - |
dc.subject.mesh | Thyroid Neoplasms - mortality - pathology | - |
dc.title | Staging systems for papillary thyroid carcinoma: A study of 2 tertiary referral centers | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lang, BHH: blang@HKUCC.hku.hk | - |
dc.identifier.email | Lo, CY: cylo@hkucc.hku.hk | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1097/01.sla.0000262785.46403.9b | - |
dc.identifier.pmid | 17592299 | - |
dc.identifier.pmcid | PMC1899202 | - |
dc.identifier.scopus | eid_2-s2.0-34347335723 | - |
dc.identifier.hkuros | 133464 | - |
dc.identifier.volume | 246 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 114 | - |
dc.identifier.epage | 121 | - |
dc.identifier.isi | WOS:000247672300018 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 0003-4932 | - |