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Conference Paper: Investigating biological mechanisms of corticosterone-induced neurodegeneration: implication of how depression promotes cognitive impairment in Alzheimer's disease
Title | Investigating biological mechanisms of corticosterone-induced neurodegeneration: implication of how depression promotes cognitive impairment in Alzheimer's disease |
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Authors | |
Keywords | Medical sciences Psychiatry and neurology gerontology and geriatrics |
Issue Date | 2013 |
Publisher | Elsevier Inc. The Journal's web site is located at http://www.alzheimersanddementia.org/ |
Citation | The 2013 International Conference of the Alzheimer’s Association (AAIC), Boston, MA., 13-18 July 2013. In Alzheimer's & Dementia, 2013, v. 9 n. 4 suppl., p. P561-P562 How to Cite? |
Abstract | BACKGROUND: It has been considered that repeated episodes of depression can promote cognitive impairment in Alzheimer's disease (AD). However, the biological mechanisms of how depression leads to cognitive impairment are largely unknown. Among different factors leading to depression, it is unclear of how increase in corticosterone leads to neurodegeneration. We hypothesize that corticosterone induces degeneration of synapses and axons in hippocampal neurons so that it promotes cognitive impairment in AD. The goal is to elucidate the pathological changes of synapses and neurites in neurons exposed to … |
Description | This journal suppl. contain abstracts of AAIC2013 |
Persistent Identifier | http://hdl.handle.net/10722/193276 |
ISSN | 2023 Impact Factor: 13.0 2023 SCImago Journal Rankings: 3.226 |
DC Field | Value | Language |
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dc.contributor.author | Chang, RCC | en_US |
dc.contributor.author | Wuwongse, S | en_US |
dc.contributor.author | Wong, S | en_US |
dc.contributor.author | Tsang, AWT | en_US |
dc.contributor.author | Zhang, E | en_US |
dc.contributor.author | Cheng, SSY | en_US |
dc.contributor.author | Hung, CHL | en_US |
dc.contributor.author | Lau, BWM | en_US |
dc.contributor.author | Ho, YS | en_US |
dc.contributor.author | So, KF | en_US |
dc.contributor.author | Law, A | en_US |
dc.date.accessioned | 2013-12-20T02:42:23Z | - |
dc.date.available | 2013-12-20T02:42:23Z | - |
dc.date.issued | 2013 | en_US |
dc.identifier.citation | The 2013 International Conference of the Alzheimer’s Association (AAIC), Boston, MA., 13-18 July 2013. In Alzheimer's & Dementia, 2013, v. 9 n. 4 suppl., p. P561-P562 | en_US |
dc.identifier.issn | 1552-5260 | - |
dc.identifier.uri | http://hdl.handle.net/10722/193276 | - |
dc.description | This journal suppl. contain abstracts of AAIC2013 | - |
dc.description.abstract | BACKGROUND: It has been considered that repeated episodes of depression can promote cognitive impairment in Alzheimer's disease (AD). However, the biological mechanisms of how depression leads to cognitive impairment are largely unknown. Among different factors leading to depression, it is unclear of how increase in corticosterone leads to neurodegeneration. We hypothesize that corticosterone induces degeneration of synapses and axons in hippocampal neurons so that it promotes cognitive impairment in AD. The goal is to elucidate the pathological changes of synapses and neurites in neurons exposed to … | - |
dc.language | eng | en_US |
dc.publisher | Elsevier Inc. The Journal's web site is located at http://www.alzheimersanddementia.org/ | - |
dc.relation.ispartof | Alzheimer's & Dementia | en_US |
dc.subject | Medical sciences | - |
dc.subject | Psychiatry and neurology gerontology and geriatrics | - |
dc.title | Investigating biological mechanisms of corticosterone-induced neurodegeneration: implication of how depression promotes cognitive impairment in Alzheimer's disease | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Chang, RCC: rccchang@hku.hk | en_US |
dc.identifier.email | Zhang, E: stonez@hku.hk | en_US |
dc.identifier.email | Hung, CHL: hungchl@hku.hk | en_US |
dc.identifier.email | Lau, BWM: bwmlau@hku.hk | en_US |
dc.identifier.email | Ho, YS: janiceys@hku.hk | en_US |
dc.identifier.email | So, KF: hrmaskf@hku.hk | en_US |
dc.identifier.email | Law, A: acklaw@hku.hk | en_US |
dc.identifier.authority | Chang, RCC=rp00470 | en_US |
dc.identifier.authority | So, KF=rp00329 | en_US |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1016/j.jalz.2013.05.1103 | - |
dc.identifier.hkuros | 227134 | en_US |
dc.identifier.volume | 9 | en_US |
dc.identifier.issue | 4 suppl. | - |
dc.identifier.spage | P561 | en_US |
dc.identifier.epage | P562 | en_US |
dc.publisher.place | United States | - |
dc.customcontrol.immutable | sml 140122 | - |
dc.identifier.issnl | 1552-5260 | - |