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- Publisher Website: 10.1159/000058363
- Scopus: eid_2-s2.0-0036284669
- PMID: 12053096
- WOS: WOS:000176409800001
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Article: Gestational diabetes mellitus and neonatal hyperthyrotropinemia
Title | Gestational diabetes mellitus and neonatal hyperthyrotropinemia |
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Authors | |
Keywords | Cord blood Gestational diabetes mellitus Newborn Thyrotropin |
Issue Date | 2002 |
Citation | Gynecologic and Obstetric Investigation, 2002, v. 53 n. 3, p. 135-139 How to Cite? |
Abstract | Objective: To determine whether gestational diabetes mellitus (GDM) is associated with increased incidence of neonatal hyperthyrotropinemia. Study Design: In a retrospective study, maternal characteristics, infant outcome and cord blood thyrotropin (TSH) concentration were compared between 469 diet-treated GDM pregnancies diagnosed by the World Health Organization 75 g oral glucose tolerance test (OGTT) with 474 non-diabetic pregnancies with normal OGTT results. Results: Hyperthyrotropinemia (TSH > 16 mIU/l) was found in 7.2% of the GDM pregnancies and 2.1% of the controls (p < 0.001), but there was no difference in the birth weight or gestational age. The TSH concentration was correlated with the OGTT 2-hour glucose value (p = 0.0948, p = 0.029) and Apgar score at the fifth minute (p = -0.1197, p = 0.009). There was no difference in the TSH or free thyroxine concentrations between the hyperthyrotropinemic newborns of the GDM and control groups. In the GDM group, the hyperthyrotropinemic newborns had a higher incidence (p = 0.017) of neonatal jaundice. Conclusions: Neonatal hyperthyrotropinemia is more frequently found in pregnancies with GDM, and this could have reflected increased fetal in-utero hypoxic stress in these pregnancies. Copyright © 2002 S. Karger AG, Basel. |
Persistent Identifier | http://hdl.handle.net/10722/194127 |
ISSN | 2023 Impact Factor: 2.0 2023 SCImago Journal Rankings: 0.579 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lao, TT | - |
dc.contributor.author | Lee, C-P | - |
dc.date.accessioned | 2014-01-30T03:32:12Z | - |
dc.date.available | 2014-01-30T03:32:12Z | - |
dc.date.issued | 2002 | - |
dc.identifier.citation | Gynecologic and Obstetric Investigation, 2002, v. 53 n. 3, p. 135-139 | - |
dc.identifier.issn | 0378-7346 | - |
dc.identifier.uri | http://hdl.handle.net/10722/194127 | - |
dc.description.abstract | Objective: To determine whether gestational diabetes mellitus (GDM) is associated with increased incidence of neonatal hyperthyrotropinemia. Study Design: In a retrospective study, maternal characteristics, infant outcome and cord blood thyrotropin (TSH) concentration were compared between 469 diet-treated GDM pregnancies diagnosed by the World Health Organization 75 g oral glucose tolerance test (OGTT) with 474 non-diabetic pregnancies with normal OGTT results. Results: Hyperthyrotropinemia (TSH > 16 mIU/l) was found in 7.2% of the GDM pregnancies and 2.1% of the controls (p < 0.001), but there was no difference in the birth weight or gestational age. The TSH concentration was correlated with the OGTT 2-hour glucose value (p = 0.0948, p = 0.029) and Apgar score at the fifth minute (p = -0.1197, p = 0.009). There was no difference in the TSH or free thyroxine concentrations between the hyperthyrotropinemic newborns of the GDM and control groups. In the GDM group, the hyperthyrotropinemic newborns had a higher incidence (p = 0.017) of neonatal jaundice. Conclusions: Neonatal hyperthyrotropinemia is more frequently found in pregnancies with GDM, and this could have reflected increased fetal in-utero hypoxic stress in these pregnancies. Copyright © 2002 S. Karger AG, Basel. | - |
dc.language | eng | - |
dc.relation.ispartof | Gynecologic and Obstetric Investigation | - |
dc.subject | Cord blood | - |
dc.subject | Gestational diabetes mellitus | - |
dc.subject | Newborn | - |
dc.subject | Thyrotropin | - |
dc.title | Gestational diabetes mellitus and neonatal hyperthyrotropinemia | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1159/000058363 | - |
dc.identifier.pmid | 12053096 | - |
dc.identifier.scopus | eid_2-s2.0-0036284669 | - |
dc.identifier.volume | 53 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 135 | - |
dc.identifier.epage | 139 | - |
dc.identifier.isi | WOS:000176409800001 | - |
dc.identifier.issnl | 0378-7346 | - |