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Conference Paper: Diffusional kurtosis imaging: towards optimal subacute assessment of the microenvironment of ischemic tissue
| Title | Diffusional kurtosis imaging: towards optimal subacute assessment of the microenvironment of ischemic tissue |
|---|---|
| Authors | |
| Issue Date | 2012 |
| Citation | The 20th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. How to Cite? |
| Abstract | The diagnostic value of ADC obtained from DWI is often dwarfed by its pseudonormalization during subacute stroke. It is therefore necessary to find an alternative that is more sensitive and specific to the underlying structural changes along the course of ischemic infarction. One potential technique is diffusion kurtosis imaging (DKI) which measures non-Gaussianity of water diffusion. The current study showed that MK is a sensitive biomarker for ischemic injury, especially subacute stroke where MD and T2W pseudonormalize as a result of vasogenic edema. DKI could potentially complement conventional DWI for improving stroke diagnosis, particularly during the subacute phase. |
| Persistent Identifier | http://hdl.handle.net/10722/195271 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hui, SK | en_US |
| dc.contributor.author | Lee, CY | en_US |
| dc.contributor.author | Debbins, JP | en_US |
| dc.contributor.author | Duong, TQ | en_US |
| dc.contributor.author | Helpern, JA | en_US |
| dc.date.accessioned | 2014-02-26T02:07:49Z | - |
| dc.date.available | 2014-02-26T02:07:49Z | - |
| dc.date.issued | 2012 | en_US |
| dc.identifier.citation | The 20th Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/195271 | - |
| dc.description.abstract | The diagnostic value of ADC obtained from DWI is often dwarfed by its pseudonormalization during subacute stroke. It is therefore necessary to find an alternative that is more sensitive and specific to the underlying structural changes along the course of ischemic infarction. One potential technique is diffusion kurtosis imaging (DKI) which measures non-Gaussianity of water diffusion. The current study showed that MK is a sensitive biomarker for ischemic injury, especially subacute stroke where MD and T2W pseudonormalize as a result of vasogenic edema. DKI could potentially complement conventional DWI for improving stroke diagnosis, particularly during the subacute phase. | en_US |
| dc.language | eng | en_US |
| dc.relation.ispartof | ISMRM 20th Annual Meeting | en_US |
| dc.title | Diffusional kurtosis imaging: towards optimal subacute assessment of the microenvironment of ischemic tissue | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.email | Hui, SK: edshui@hku.hk | en_US |
| dc.identifier.authority | Hui, SK=rp01832 | en_US |