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Conference Paper: Comparing illness presentation, treatment and functioning between patients with early- and adult-onset psychosis
Title | Comparing illness presentation, treatment and functioning between patients with early- and adult-onset psychosis |
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Authors | |
Issue Date | 2014 |
Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres |
Citation | The 4th Biennial Schizophrenia International Research Conference, Florence, Italy, 5-9 April 2014. In Schizophrenia Research, 2014, v. 153 suppl. 1, p. S263-S264, poster no. M202 How to Cite? |
Abstract | BACKGROUND: Early studies have shown that patients with early- and adult-onset schizophrenia differ in their illness presentation, psychopathology, pre-morbid traits and prognosis. Whether adult-onset schizophrenia represents a separate entity distinct from early-onset schizophrenia is yet uncertain. Therefore, the current study aimed at characterizing and contrasting adult-onset patients with an early-onset cohort in their basic demographics, illness presentation, treatment and functional level. METHODS: Participants were recruited from two territory-wide early intervention services for early-onset (n=671; from the Early Assessment Service for Young People with Psychosis Program, EASY) and late-onset psychosis patients (n=360; from the Jockey Club Early Psychosis Project, JCEP) in Hong Kong. Patients from the early-onset cohort had their initial psychotic episode during 2001 and 2003; data were then collected retrospectively by systematic case note review. The adult-onset cohort was prospectively recruited as part of a larger interventional study during 2009 and 2011; information was collected prospectively via face-to-face interviews with patients. RESULTS: At baseline, adult-onset psychosis (mean of 36.6 years old) was significantly associated with more females, more non-local birth, more full-time employment, better functioning level, fewer smokers, fewer with schizophrenia than early-onset psychosis (mean of 20.4 years old), better medication adherence and more psychiatric hospitalization. No significant group differences in duration of untreated psychosis were found. DISCUSSION: Managing psychotic illnesses optimally is an important challenge in health care delivery. The finding that adult-onset patients had better functioning challenges the view that early-onset psychosis and adult-onset psychosis share a similar prognostic trajectory. There is a need to adapt intervention processes, specifically for patients recovering from a first episode illness, in particular for early- and adult-onset, as they may face different unique sets of challenges. |
Description | This journal suppl. entitled: Abstracts of the 4th Biennial Schizophrenia International Research Conference |
Persistent Identifier | http://hdl.handle.net/10722/197869 |
ISSN | 2023 Impact Factor: 3.6 2023 SCImago Journal Rankings: 1.374 |
DC Field | Value | Language |
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dc.contributor.author | Hui, CLM | en_US |
dc.contributor.author | Chang, WC | en_US |
dc.contributor.author | Chan, KW | en_US |
dc.contributor.author | Lee, HME | en_US |
dc.contributor.author | Chen, EYH | en_US |
dc.date.accessioned | 2014-06-02T15:20:39Z | - |
dc.date.available | 2014-06-02T15:20:39Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | The 4th Biennial Schizophrenia International Research Conference, Florence, Italy, 5-9 April 2014. In Schizophrenia Research, 2014, v. 153 suppl. 1, p. S263-S264, poster no. M202 | en_US |
dc.identifier.issn | 0920-9964 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/197869 | - |
dc.description | This journal suppl. entitled: Abstracts of the 4th Biennial Schizophrenia International Research Conference | - |
dc.description.abstract | BACKGROUND: Early studies have shown that patients with early- and adult-onset schizophrenia differ in their illness presentation, psychopathology, pre-morbid traits and prognosis. Whether adult-onset schizophrenia represents a separate entity distinct from early-onset schizophrenia is yet uncertain. Therefore, the current study aimed at characterizing and contrasting adult-onset patients with an early-onset cohort in their basic demographics, illness presentation, treatment and functional level. METHODS: Participants were recruited from two territory-wide early intervention services for early-onset (n=671; from the Early Assessment Service for Young People with Psychosis Program, EASY) and late-onset psychosis patients (n=360; from the Jockey Club Early Psychosis Project, JCEP) in Hong Kong. Patients from the early-onset cohort had their initial psychotic episode during 2001 and 2003; data were then collected retrospectively by systematic case note review. The adult-onset cohort was prospectively recruited as part of a larger interventional study during 2009 and 2011; information was collected prospectively via face-to-face interviews with patients. RESULTS: At baseline, adult-onset psychosis (mean of 36.6 years old) was significantly associated with more females, more non-local birth, more full-time employment, better functioning level, fewer smokers, fewer with schizophrenia than early-onset psychosis (mean of 20.4 years old), better medication adherence and more psychiatric hospitalization. No significant group differences in duration of untreated psychosis were found. DISCUSSION: Managing psychotic illnesses optimally is an important challenge in health care delivery. The finding that adult-onset patients had better functioning challenges the view that early-onset psychosis and adult-onset psychosis share a similar prognostic trajectory. There is a need to adapt intervention processes, specifically for patients recovering from a first episode illness, in particular for early- and adult-onset, as they may face different unique sets of challenges. | - |
dc.language | eng | en_US |
dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres | en_US |
dc.relation.ispartof | Schizophrenia Research | en_US |
dc.title | Comparing illness presentation, treatment and functioning between patients with early- and adult-onset psychosis | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Hui, CLM: christyh@hkucc.hku.hk | en_US |
dc.identifier.email | Chang, WC: changwc@hku.hk | en_US |
dc.identifier.email | Chan, KW: kwsherry@hku.hk | en_US |
dc.identifier.email | Lee, HME: edwinlhm@hku.hk | en_US |
dc.identifier.email | Chen, EYH: eyhchen@hku.hk | en_US |
dc.identifier.authority | Chang, WC=rp01465 | en_US |
dc.identifier.authority | Chan, KW=rp00539 | en_US |
dc.identifier.authority | Lee, HME=rp01575 | en_US |
dc.identifier.authority | Chen, EYH=rp00392 | en_US |
dc.identifier.doi | 10.1016/S0920-9964(14)70752-2 | - |
dc.identifier.hkuros | 229037 | en_US |
dc.identifier.hkuros | 249086 | - |
dc.identifier.volume | 153 | en_US |
dc.identifier.issue | suppl. 1 | en_US |
dc.identifier.spage | S263, poster no. M202 | en_US |
dc.identifier.epage | S264 | en_US |
dc.publisher.place | The Netherlands | en_US |
dc.identifier.issnl | 0920-9964 | - |