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- Publisher Website: 10.5603/CJ.a2014.0034
- Scopus: eid_2-s2.0-84908296715
- PMID: 24846512
- WOS: WOS:000345995800005
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Article: Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke
Title | Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke |
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Authors | |
Keywords | CHADS2 CHA2DS2-VASc Atrial fibrillation Myocardial infarction |
Issue Date | 2014 |
Publisher | Via Medica. The Journal's web site is located at http://czasopisma.viamedica.pl/cj |
Citation | Cardiology Journal, 2014, v. 21 n. 5, p. 474-483 How to Cite? |
Abstract | Background: Patients with myocardial infarction (MI) are at risk of the development of atrial fibrillation (AF) and ischemic stroke. We sought to evaluate the prognostic performance of the CHADS2 and CHA2DS2-VASc scores in predicting new AF and/or ischemic stroke in post-ST segment elevation MI (STEMI) patients. Six hundred and seven consecutive post-STEMI patients with no previously documented AF were studied.
Methods and Results: After a follow-up of 63 months (3,184 patient-years), 83 (13.7%) patients developed new AF (2.8% per year). Patients with a high CHADS2 and/or CHA2DS2-VASc score were more likely to develop new AF. The annual incidence of new AF was 1.18%, 2.10%, 4.52%, and 7.03% in patients with CHADS2 of 0, 1, 2, and ≥ 3; and 0.39%, 1.72%, 1.83%, and 5.83% in patients with a CHA2DS2-VASc score of 1, 2, 3 and ≥ 4. The CHA2DS2-VASc score (C-statistic = 0.676) was superior to the CHADS2 (C-statistic = 0.632) for discriminating new AF. Ischemic stroke occurred in 29 patients (0.9% per year), the incidence increasing in line with the CHADS2 (0.41%, 1.02%, 1.11%, and 1.95% with score of 0, 1, 2, and ≥ 3) and CHA2DS2-VASc scores (0.39%, 0.49%, 1.02%, and 1.48% with score of 1, 2, 3 and ≥ 4). The C-statistic of the CHA2DS2-VASc score as a predictor of ischemic stroke was 0.601, superior to that of CHADS2 score (0.573). CHADS2 and CHA2DS2-VASc scores can identify post-STEMI patients at high risk of AF and stroke.
Conclusions: The CHADS2 and CHA2DS2-VASc scores can identify post-STEMI patients at high risk of AF and ischemic stroke. This enables close surveillance and prompt anticoagulation for stroke prevention. |
Persistent Identifier | http://hdl.handle.net/10722/198039 |
ISSN | 2023 Impact Factor: 2.5 2023 SCImago Journal Rankings: 0.611 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lau, GKK | - |
dc.contributor.author | Chan, PHM | - |
dc.contributor.author | Yiu, KH | - |
dc.contributor.author | Chan, YH | - |
dc.contributor.author | Liu, S | - |
dc.contributor.author | Chan, KH | - |
dc.contributor.author | Yeung, CY | - |
dc.contributor.author | Li, LSW | - |
dc.contributor.author | Tse, HF | - |
dc.contributor.author | Siu, DCW | - |
dc.date.accessioned | 2014-06-25T02:42:06Z | - |
dc.date.available | 2014-06-25T02:42:06Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Cardiology Journal, 2014, v. 21 n. 5, p. 474-483 | - |
dc.identifier.issn | 1897-5593 | - |
dc.identifier.uri | http://hdl.handle.net/10722/198039 | - |
dc.description.abstract | Background: Patients with myocardial infarction (MI) are at risk of the development of atrial fibrillation (AF) and ischemic stroke. We sought to evaluate the prognostic performance of the CHADS2 and CHA2DS2-VASc scores in predicting new AF and/or ischemic stroke in post-ST segment elevation MI (STEMI) patients. Six hundred and seven consecutive post-STEMI patients with no previously documented AF were studied. Methods and Results: After a follow-up of 63 months (3,184 patient-years), 83 (13.7%) patients developed new AF (2.8% per year). Patients with a high CHADS2 and/or CHA2DS2-VASc score were more likely to develop new AF. The annual incidence of new AF was 1.18%, 2.10%, 4.52%, and 7.03% in patients with CHADS2 of 0, 1, 2, and ≥ 3; and 0.39%, 1.72%, 1.83%, and 5.83% in patients with a CHA2DS2-VASc score of 1, 2, 3 and ≥ 4. The CHA2DS2-VASc score (C-statistic = 0.676) was superior to the CHADS2 (C-statistic = 0.632) for discriminating new AF. Ischemic stroke occurred in 29 patients (0.9% per year), the incidence increasing in line with the CHADS2 (0.41%, 1.02%, 1.11%, and 1.95% with score of 0, 1, 2, and ≥ 3) and CHA2DS2-VASc scores (0.39%, 0.49%, 1.02%, and 1.48% with score of 1, 2, 3 and ≥ 4). The C-statistic of the CHA2DS2-VASc score as a predictor of ischemic stroke was 0.601, superior to that of CHADS2 score (0.573). CHADS2 and CHA2DS2-VASc scores can identify post-STEMI patients at high risk of AF and stroke. Conclusions: The CHADS2 and CHA2DS2-VASc scores can identify post-STEMI patients at high risk of AF and ischemic stroke. This enables close surveillance and prompt anticoagulation for stroke prevention. | - |
dc.language | eng | - |
dc.publisher | Via Medica. The Journal's web site is located at http://czasopisma.viamedica.pl/cj | - |
dc.relation.ispartof | Cardiology Journal | - |
dc.subject | CHADS2 | - |
dc.subject | CHA2DS2-VASc | - |
dc.subject | Atrial fibrillation | - |
dc.subject | Myocardial infarction | - |
dc.title | Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke | - |
dc.type | Article | - |
dc.identifier.email | Lau, GKK: gkklau@hku.hk | - |
dc.identifier.email | Chan, PHM: phmchan@hku.hk | - |
dc.identifier.email | Yiu, KH: khkyiu@hku.hk | - |
dc.identifier.email | Chan, YH: chanwill@hku.hk | - |
dc.identifier.email | Liu, S: shasha99@hku.hk | - |
dc.identifier.email | Chan, KH: koonho@hku.hk | - |
dc.identifier.email | Yeung, CY: ycy167@hku.hk | - |
dc.identifier.email | Li, LSW: lswli@hkucc.hku.hk | - |
dc.identifier.email | Tse, HF: hftse@hkucc.hku.hk | - |
dc.identifier.email | Siu, DCW: cwdsiu@hkucc.hku.hk | - |
dc.identifier.authority | Lau, GKK=rp01499 | - |
dc.identifier.authority | Chan, PHM=rp01864 | - |
dc.identifier.authority | Yiu, KH=rp01490 | - |
dc.identifier.authority | Chan, YH=rp01313 | - |
dc.identifier.authority | Liu, S=rp01628 | - |
dc.identifier.authority | Chan, KH=rp00537 | - |
dc.identifier.authority | Tse, HF=rp00428 | - |
dc.identifier.authority | Siu, DCW=rp00534 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.5603/CJ.a2014.0034 | - |
dc.identifier.pmid | 24846512 | - |
dc.identifier.scopus | eid_2-s2.0-84908296715 | - |
dc.identifier.hkuros | 229236 | - |
dc.identifier.volume | 21 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 474 | - |
dc.identifier.epage | 483 | - |
dc.identifier.isi | WOS:000345995800005 | - |
dc.publisher.place | Poland | - |
dc.identifier.issnl | 1898-018X | - |