File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.13748/j.cnki.issn1007-7693.2014.05.009
- Find via
Supplementary
-
Citations:
- Appears in Collections:
Article: Purification of Z-Ligustilide by AgNO3-Impregnated Silica Gel
Title | Purification of Z-Ligustilide by AgNO3-Impregnated Silica Gel 硝酸银改性硅胶柱色谱法纯化川芎精油中的藁本内酯 |
---|---|
Authors | |
Issue Date | 2014 |
Publisher | Chinese Pharmaceutical Association. The Journal's web site is located at http://www.chinjmap.com/ch/index.aspx |
Citation | Chinese Journal of Modern Applied Pharmacy, 2014, v. 31 n. 5, p. 552-555 How to Cite? 中国现代应用药学, 2014, v. 31 n. 5, p. 552-555 How to Cite? |
Abstract | OBJECTIVE To investigate the application of AgNO3-impregnated silica gel in a format of column chromatography for the isolation and purification of Z-ligustilide from the essential oil of Ligusticum chuanxiong Hort.. METHODS AgNO3(2%) was impregnated to the common silica gel to generate a new column chromatographic media. The essential oil was eluted with the mobile phase (petroleum ether: acetoacetate=98.5∶1.5), and detected by TLC and UV-Vis spectrometer. The product Z-ligustilide was characterized by GC-MS and HPLC techniques. RESULTS Z-Ligustilide with the purity of 98.87% was effectively purified. CONCLUSION The present study describes a method for rapid isolation of highly pure Z-ligustilide at low cost, allowing future scale-up for modern industrial production. |
Persistent Identifier | http://hdl.handle.net/10722/198262 |
ISSN | 2023 SCImago Journal Rankings: 0.144 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | CHENG, Y | en_US |
dc.contributor.author | YANG, C | en_US |
dc.contributor.author | ZHAO, J | en_US |
dc.contributor.author | Rong, J | en_US |
dc.date.accessioned | 2014-06-25T02:58:01Z | - |
dc.date.available | 2014-06-25T02:58:01Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | Chinese Journal of Modern Applied Pharmacy, 2014, v. 31 n. 5, p. 552-555 | en_US |
dc.identifier.citation | 中国现代应用药学, 2014, v. 31 n. 5, p. 552-555 | en_US |
dc.identifier.issn | 1007-7693 | - |
dc.identifier.uri | http://hdl.handle.net/10722/198262 | - |
dc.description.abstract | OBJECTIVE To investigate the application of AgNO3-impregnated silica gel in a format of column chromatography for the isolation and purification of Z-ligustilide from the essential oil of Ligusticum chuanxiong Hort.. METHODS AgNO3(2%) was impregnated to the common silica gel to generate a new column chromatographic media. The essential oil was eluted with the mobile phase (petroleum ether: acetoacetate=98.5∶1.5), and detected by TLC and UV-Vis spectrometer. The product Z-ligustilide was characterized by GC-MS and HPLC techniques. RESULTS Z-Ligustilide with the purity of 98.87% was effectively purified. CONCLUSION The present study describes a method for rapid isolation of highly pure Z-ligustilide at low cost, allowing future scale-up for modern industrial production. | en_US |
dc.language | chi | en_US |
dc.publisher | Chinese Pharmaceutical Association. The Journal's web site is located at http://www.chinjmap.com/ch/index.aspx | - |
dc.relation.ispartof | Chinese Journal of Modern Applied Pharmacy | en_US |
dc.relation.ispartof | 中国现代应用药学 | en_US |
dc.title | Purification of Z-Ligustilide by AgNO3-Impregnated Silica Gel | en_US |
dc.title | 硝酸银改性硅胶柱色谱法纯化川芎精油中的藁本内酯 | en_US |
dc.type | Article | en_US |
dc.identifier.email | Rong, J: jrong@hku.hk | en_US |
dc.identifier.authority | Rong, J=rp00515 | en_US |
dc.identifier.doi | 10.13748/j.cnki.issn1007-7693.2014.05.009 | en_US |
dc.identifier.hkuros | 229446 | en_US |
dc.identifier.volume | 31 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.spage | 552 | en_US |
dc.identifier.epage | 555 | en_US |
dc.identifier.issnl | 1007-7693 | - |