File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1016/j.ces.2014.05.037
- Scopus: eid_2-s2.0-85027947047
- WOS: WOS:000349447500021
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Electrostatics in pharmaceutical solids
Title | Electrostatics in pharmaceutical solids |
---|---|
Authors | |
Keywords | Aerosols Electrostatic charge Inhalation Pharmaceutical industry Pharmaceuticals Triboelectrification |
Issue Date | 2015 |
Publisher | Pergamon. The Journal's web site is located at http://www.elsevier.com/locate/ces |
Citation | Chemical Engineering Science, 2015, v. 125, p. 225-237 How to Cite? |
Abstract | Pharmaceutical solids are likely to accumulate electrostatic charge through handling processes encountered both in industry and during clinical use. Important advances in the past decade have continued to improve our understanding and enabled better control of electrostatics. Although certain areas have been studied more extensively than others, much remains unexplored at the fundamental level and in vivo deposition studies are required to confirm the impact of charged aerosols in humans. This review has summarised the key fundamentals, highlighted the relevance in industrial and clinical settings, evaluated the factors that influence charging and discussed measurement techniques with regards to pharmaceutical powders. The understanding gained could potentially have regulatory implications, and could assist in the development and manufacture of pharmaceutical powders and their delivery systems. © 2014 Elsevier B.V. |
Persistent Identifier | http://hdl.handle.net/10722/203286 |
ISSN | 2023 Impact Factor: 4.1 2023 SCImago Journal Rankings: 0.817 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wong, J | - |
dc.contributor.author | Kwok, PCL | - |
dc.contributor.author | Chan, HK | - |
dc.date.accessioned | 2014-09-19T13:56:09Z | - |
dc.date.available | 2014-09-19T13:56:09Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Chemical Engineering Science, 2015, v. 125, p. 225-237 | - |
dc.identifier.issn | 0009-2509 | - |
dc.identifier.uri | http://hdl.handle.net/10722/203286 | - |
dc.description.abstract | Pharmaceutical solids are likely to accumulate electrostatic charge through handling processes encountered both in industry and during clinical use. Important advances in the past decade have continued to improve our understanding and enabled better control of electrostatics. Although certain areas have been studied more extensively than others, much remains unexplored at the fundamental level and in vivo deposition studies are required to confirm the impact of charged aerosols in humans. This review has summarised the key fundamentals, highlighted the relevance in industrial and clinical settings, evaluated the factors that influence charging and discussed measurement techniques with regards to pharmaceutical powders. The understanding gained could potentially have regulatory implications, and could assist in the development and manufacture of pharmaceutical powders and their delivery systems. © 2014 Elsevier B.V. | - |
dc.language | eng | - |
dc.publisher | Pergamon. The Journal's web site is located at http://www.elsevier.com/locate/ces | - |
dc.relation.ispartof | Chemical Engineering Science | - |
dc.subject | Aerosols | - |
dc.subject | Electrostatic charge | - |
dc.subject | Inhalation | - |
dc.subject | Pharmaceutical industry | - |
dc.subject | Pharmaceuticals | - |
dc.subject | Triboelectrification | - |
dc.title | Electrostatics in pharmaceutical solids | - |
dc.type | Article | - |
dc.identifier.email | Kwok, PCL: pclkwok@hku.hk | - |
dc.identifier.email | Chan, HK: kimchan1@hku.hk | - |
dc.identifier.authority | Kwok, PCL=rp01540 | - |
dc.identifier.doi | 10.1016/j.ces.2014.05.037 | - |
dc.identifier.scopus | eid_2-s2.0-85027947047 | - |
dc.identifier.hkuros | 236954 | - |
dc.identifier.volume | 125 | - |
dc.identifier.spage | 225 | - |
dc.identifier.epage | 237 | - |
dc.identifier.isi | WOS:000349447500021 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 0009-2509 | - |