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Conference Paper: Visit-to-visit blood pressure variability is associated with periventricular white matter hyperintensity in healthy hypertensive elderly Chinese
Title | Visit-to-visit blood pressure variability is associated with periventricular white matter hyperintensity in healthy hypertensive elderly Chinese |
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Authors | |
Issue Date | 2014 |
Publisher | Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk |
Citation | The 19th Medical Research Conference (MRC 2014), Department of Medicine, The University of Hong Kong, Hong Kong, China, 18 January 2014. In Hong Kong Medical Journal, 2014, v. 20 suppl. 1. p. 46, abstract no. 76 How to Cite? |
Abstract | Background: Visit-to-visit blood pressure variability (BPV) has been reported to be associated with the severity
and prognosis of symptomatic stroke, but its correlation with silent stroke is unclear. We aimed to evaluate the
relationship between BPV and silent cerebral vascular lesions (SCVL).
Methods: A total of 239 healthy hypertensive Chinese aged more than 65 years were recruited. SCVLs including
silent brain infarcts (BIs), microbleeds (MBs), and white matter hyperintensity (WMH) were determined by
magnetic resonance images on a 3T scanner. The severity of WMH was rated using the Fazekas white matter
scale. Previous 3-year blood pressure measurements were collected from the electronic medical record.
BPV parameters—including standard deviation, coefficient of variation, successive variation, and variation
independent of mean blood pressure—were calculated. Statistical analyses were performed to evaluate the
significance of relationships.
Result: Of the patients, 26 (10.9%) and 12 (5.0%) had severe periventricular WMH and deep WMH (Fazekas score
= 3), respectively. Both systolic and diastolic BPV parameters were correlated with the severity of periventricular
WMH (P < 0.05) but not the severity of deep WMH, presence of BIs or MBs. The relationship between BPV
parameters and periventricular WMH still existed after adjustment for age and other factors.
Conclusion: BPV was an independent predictor of severe periventricular WMH in healthy hypertensive elderly. |
Description | Oral Presentation |
Persistent Identifier | http://hdl.handle.net/10722/203985 |
ISSN | 2023 Impact Factor: 3.1 2023 SCImago Journal Rankings: 0.261 |
DC Field | Value | Language |
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dc.contributor.author | Xoe, B | en_US |
dc.contributor.author | Zhang, M | en_US |
dc.contributor.author | Mak, HKF | en_US |
dc.contributor.author | Cheung, RTF | en_US |
dc.date.accessioned | 2014-09-19T19:48:25Z | - |
dc.date.available | 2014-09-19T19:48:25Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | The 19th Medical Research Conference (MRC 2014), Department of Medicine, The University of Hong Kong, Hong Kong, China, 18 January 2014. In Hong Kong Medical Journal, 2014, v. 20 suppl. 1. p. 46, abstract no. 76 | en_US |
dc.identifier.issn | 1024-2708 | - |
dc.identifier.uri | http://hdl.handle.net/10722/203985 | - |
dc.description | Oral Presentation | - |
dc.description.abstract | Background: Visit-to-visit blood pressure variability (BPV) has been reported to be associated with the severity and prognosis of symptomatic stroke, but its correlation with silent stroke is unclear. We aimed to evaluate the relationship between BPV and silent cerebral vascular lesions (SCVL). Methods: A total of 239 healthy hypertensive Chinese aged more than 65 years were recruited. SCVLs including silent brain infarcts (BIs), microbleeds (MBs), and white matter hyperintensity (WMH) were determined by magnetic resonance images on a 3T scanner. The severity of WMH was rated using the Fazekas white matter scale. Previous 3-year blood pressure measurements were collected from the electronic medical record. BPV parameters—including standard deviation, coefficient of variation, successive variation, and variation independent of mean blood pressure—were calculated. Statistical analyses were performed to evaluate the significance of relationships. Result: Of the patients, 26 (10.9%) and 12 (5.0%) had severe periventricular WMH and deep WMH (Fazekas score = 3), respectively. Both systolic and diastolic BPV parameters were correlated with the severity of periventricular WMH (P < 0.05) but not the severity of deep WMH, presence of BIs or MBs. The relationship between BPV parameters and periventricular WMH still existed after adjustment for age and other factors. Conclusion: BPV was an independent predictor of severe periventricular WMH in healthy hypertensive elderly. | - |
dc.language | eng | en_US |
dc.publisher | Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk | - |
dc.relation.ispartof | Hong Kong Medical Journal | en_US |
dc.rights | Hong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.title | Visit-to-visit blood pressure variability is associated with periventricular white matter hyperintensity in healthy hypertensive elderly Chinese | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Mak, HKF: makkf@hkucc.hku.hk | en_US |
dc.identifier.email | Cheung, RTF: rtcheung@hku.hk | en_US |
dc.identifier.authority | Mak, HKF=rp00533 | en_US |
dc.identifier.authority | Cheung, RTF=rp00434 | en_US |
dc.description.nature | published_or_final_version | - |
dc.identifier.hkuros | 236232 | en_US |
dc.identifier.volume | 20 | en_US |
dc.identifier.issue | suppl. 1 | en_US |
dc.identifier.spage | 46, abstract no. 76 | en_US |
dc.identifier.epage | 46, abstract no. 76 | en_US |
dc.publisher.place | Hong Kong | - |
dc.identifier.issnl | 1024-2708 | - |