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Article: Advances in the recent research on correlation between Th1/Th17-related cytokines and autoimmune uveitis
Title | Advances in the recent research on correlation between Th1/Th17-related cytokines and autoimmune uveitis 自身免疫性葡萄膜炎與Th1、Th17相關細胞因數的研究進展 |
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Authors | |
Keywords | Uveitis/immunology (葡萄膜炎/免疫) Autoimmune (自身免疫) CD4+T (輔助性T細胞) Helper Cytokine (細胞因數) |
Issue Date | 2014 |
Publisher | Chinese Medical Association (中華醫學會). The Journal's web site is located at http://c.g.wanfangdata.com.cn/Periodical-ykyj.aspx |
Citation | Chinese Journal of Experimental Ophthalmology, 2014, v. 32 n. 10, p. 943-949 How to Cite? 中華實驗眼科雜誌, 2014, v. 32 n. 10, p. 943-949 How to Cite? |
Abstract | 人類自身免疫性葡萄膜炎是一組常見的眼部炎症性疾病,不明因素導致的自身免疫紊亂可對眼部組織產生不可逆性損害,因此長期以來,對人類自身免疫性葡萄膜炎的致病原因、發病機制的研究從未停止.以往的研究認為,1型輔助性T細胞群(Th1)是誘發人類自身免疫性葡萄膜炎的關鍵因素,但近年來發現,Th17是誘導自身免疫性葡萄膜炎病變的主要因素.由於每種Th細胞群都有其特定的細胞因數及轉錄因數,這些細胞因數通過調節Th1、Th2、Th17的表達及平衡決定著自身免疫性葡萄膜炎的發生和發展.研究Th1及Th17相關細胞因數在病變中的作用是探討自身免疫性葡萄膜炎發生和發展的重要基礎之一.就近年來Th1及Th17主要的相關細胞因數在葡萄膜炎的致病性、調節及治療作用方面的研究進展進行綜述 |
Persistent Identifier | http://hdl.handle.net/10722/205562 |
ISSN | 2023 SCImago Journal Rankings: 0.140 |
DC Field | Value | Language |
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dc.contributor.author | Chen, W | - |
dc.contributor.author | Chen, L | - |
dc.date.accessioned | 2014-09-20T04:00:21Z | - |
dc.date.available | 2014-09-20T04:00:21Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Chinese Journal of Experimental Ophthalmology, 2014, v. 32 n. 10, p. 943-949 | - |
dc.identifier.citation | 中華實驗眼科雜誌, 2014, v. 32 n. 10, p. 943-949 | - |
dc.identifier.issn | 2095-0160 | - |
dc.identifier.uri | http://hdl.handle.net/10722/205562 | - |
dc.description.abstract | 人類自身免疫性葡萄膜炎是一組常見的眼部炎症性疾病,不明因素導致的自身免疫紊亂可對眼部組織產生不可逆性損害,因此長期以來,對人類自身免疫性葡萄膜炎的致病原因、發病機制的研究從未停止.以往的研究認為,1型輔助性T細胞群(Th1)是誘發人類自身免疫性葡萄膜炎的關鍵因素,但近年來發現,Th17是誘導自身免疫性葡萄膜炎病變的主要因素.由於每種Th細胞群都有其特定的細胞因數及轉錄因數,這些細胞因數通過調節Th1、Th2、Th17的表達及平衡決定著自身免疫性葡萄膜炎的發生和發展.研究Th1及Th17相關細胞因數在病變中的作用是探討自身免疫性葡萄膜炎發生和發展的重要基礎之一.就近年來Th1及Th17主要的相關細胞因數在葡萄膜炎的致病性、調節及治療作用方面的研究進展進行綜述 | - |
dc.language | chi | - |
dc.publisher | Chinese Medical Association (中華醫學會). The Journal's web site is located at http://c.g.wanfangdata.com.cn/Periodical-ykyj.aspx | - |
dc.relation.ispartof | Chinese Journal of Experimental Ophthalmology | - |
dc.relation.ispartof | 中華實驗眼科雜誌 | - |
dc.subject | Uveitis/immunology (葡萄膜炎/免疫) | - |
dc.subject | Autoimmune (自身免疫) | - |
dc.subject | CD4+T (輔助性T細胞) | - |
dc.subject | Helper Cytokine (細胞因數) | - |
dc.title | Advances in the recent research on correlation between Th1/Th17-related cytokines and autoimmune uveitis | - |
dc.title | 自身免疫性葡萄膜炎與Th1、Th17相關細胞因數的研究進展 | - |
dc.type | Article | - |
dc.identifier.email | Chen, L: lchen98@hku.hk | - |
dc.identifier.authority | Chen, L=rp01865 | - |
dc.identifier.doi | 10.3760/cma.j.issn.2095-0160.2014.10.017 | - |
dc.identifier.scopus | eid_2-s2.0-84908091905 | - |
dc.identifier.hkuros | 237194 | - |
dc.identifier.volume | 32 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | 943 | - |
dc.identifier.epage | 949 | - |
dc.publisher.place | China (中國) | - |
dc.customcontrol.immutable | csl 150409 | - |
dc.identifier.issnl | 2095-0160 | - |