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Conference Paper: The efficacy of treating normal tension glaucoma with a single session of selective laser trabeculoplasty
Title | The efficacy of treating normal tension glaucoma with a single session of selective laser trabeculoplasty |
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Authors | |
Issue Date | 2014 |
Citation | The 2nd Asia-Pacific Glaucoma Congress in conjunction with the 10th International Symposium of Ophthalmology - Hong Kong (APGC / ISOHK 2014), Hong Kong, China, 26-28 September 2014. How to Cite? |
Abstract | PURPOSE: The purpose of this study was to investigate the efficacy of selective laser trabeculoplasty (SLT) in the treatment of normal tension glaucoma (NTG). METHODS: This prospective cohort study recruited consecutive cases of NTG on antiglaucoma medication. Cases were excluded for previous glaucoma surgery or laser. All patients underwent a 1-month washout of medication followed by a mean baseline intraocular pressure (IOP) measured at 9 AM, 1 PM, and 5 PM. A 30% reduction from baseline was set as the target IOP. A single session of SLT was performed to 360 degrees of the trabecular meshwork. IOP phasing was repeated at 1 month after SLT and medication was resumed to achieve the target IOP. Patients were followed up to 6 months after SLT. RESULTS: In 83 eyes of 46 subjects, the mean prestudy IOP was 14.2 ± 3.1 mm Hg when on 1.5 ± 0.9 antiglaucoma medication. The mean baseline IOP without medication was 16.1 ± 2.2 mm Hg. The mean SLT shots applied was 187.8 ± 27.5 using a mean energy of 1.0 ± 0.07 mJ. At 1-month post-SLT, the IOP was 12.7 ± 2.0 mm Hg (21.6% IOP reduction) from baseline without medication (P<0.05). The 6-month IOP was 11.4 ± 1.6 mm Hg when on 1.1± 1.0 medications, representing a 19.7% reduction from prestudy IOP, a 29.6% reduction from baseline IOP, and a 26.7% reduction in antiglaucoma medication (all P< 0.05). A higher baseline IOP was correlated with greater IOP reduction with SLT (r=0.3, P=0.009). CONCLUSIONS: A single session of SLT for NTG achieved an additional 20% reduction in IOP with 27% less medication at 6 months compared with prestudy levels while maintaining a 30% reduction from baseline IOP. |
Description | Symposium: NTG update |
Persistent Identifier | http://hdl.handle.net/10722/208666 |
DC Field | Value | Language |
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dc.contributor.author | Lee, WYJ | - |
dc.contributor.author | Gangwani, RA | - |
dc.contributor.author | Chan, JC | - |
dc.contributor.author | Lai, JSM | - |
dc.date.accessioned | 2015-03-18T07:18:21Z | - |
dc.date.available | 2015-03-18T07:18:21Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | The 2nd Asia-Pacific Glaucoma Congress in conjunction with the 10th International Symposium of Ophthalmology - Hong Kong (APGC / ISOHK 2014), Hong Kong, China, 26-28 September 2014. | - |
dc.identifier.uri | http://hdl.handle.net/10722/208666 | - |
dc.description | Symposium: NTG update | - |
dc.description.abstract | PURPOSE: The purpose of this study was to investigate the efficacy of selective laser trabeculoplasty (SLT) in the treatment of normal tension glaucoma (NTG). METHODS: This prospective cohort study recruited consecutive cases of NTG on antiglaucoma medication. Cases were excluded for previous glaucoma surgery or laser. All patients underwent a 1-month washout of medication followed by a mean baseline intraocular pressure (IOP) measured at 9 AM, 1 PM, and 5 PM. A 30% reduction from baseline was set as the target IOP. A single session of SLT was performed to 360 degrees of the trabecular meshwork. IOP phasing was repeated at 1 month after SLT and medication was resumed to achieve the target IOP. Patients were followed up to 6 months after SLT. RESULTS: In 83 eyes of 46 subjects, the mean prestudy IOP was 14.2 ± 3.1 mm Hg when on 1.5 ± 0.9 antiglaucoma medication. The mean baseline IOP without medication was 16.1 ± 2.2 mm Hg. The mean SLT shots applied was 187.8 ± 27.5 using a mean energy of 1.0 ± 0.07 mJ. At 1-month post-SLT, the IOP was 12.7 ± 2.0 mm Hg (21.6% IOP reduction) from baseline without medication (P<0.05). The 6-month IOP was 11.4 ± 1.6 mm Hg when on 1.1± 1.0 medications, representing a 19.7% reduction from prestudy IOP, a 29.6% reduction from baseline IOP, and a 26.7% reduction in antiglaucoma medication (all P< 0.05). A higher baseline IOP was correlated with greater IOP reduction with SLT (r=0.3, P=0.009). CONCLUSIONS: A single session of SLT for NTG achieved an additional 20% reduction in IOP with 27% less medication at 6 months compared with prestudy levels while maintaining a 30% reduction from baseline IOP. | - |
dc.language | eng | - |
dc.relation.ispartof | APGC / ISOHK 2014 | - |
dc.title | The efficacy of treating normal tension glaucoma with a single session of selective laser trabeculoplasty | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Lee, WYJ: jackylee@hku.hk | - |
dc.identifier.email | Gangwani, RA: gangwani@hku.hk | - |
dc.identifier.email | Lai, JSM: laism@hku.hk | - |