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- Publisher Website: 10.1016/j.jamda.2015.03.005
- Scopus: eid_2-s2.0-84929951367
- WOS: WOS:000355134100022
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Article: Toward a Comprehensive Model of Frailty: An Emerging Concept From the Hong Kong Centenarian Study
Title | Toward a Comprehensive Model of Frailty: An Emerging Concept From the Hong Kong Centenarian Study |
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Authors | |
Keywords | Aging Centenarians Frailty Multidisciplinary Psychosocial |
Issue Date | 2015 |
Citation | Journal of the American Medical Directors Association, 2015, v. 16 n. 6, p. 536.e1-536.e7 How to Cite? |
Abstract | OBJECTIVES: A better understanding of the essential components of frailty is important for future developments of management strategies. We aimed to assess the incremental validity of a Comprehensive Model of Frailty (CMF) over Frailty Index (FI) in predicting self-rated health and functional dependency amongst near-centenarians and centenarians. DESIGN: Cross-sectional, community-based study. SETTING: Two community-based social and clinical networks. PARTICIPANTS: One hundred twenty-four community-dwelling Chinese near-centenarians and centenarians. MEASUREMENTS: Frailty was first assessed using a 32-item FI (FI-32). Then, a new CMF was constructed by adding 12 items in the psychological, social/family, environmental, and economic domains to the FI-32. Hierarchical multiple regressions explored whether the new CMF provided significant additional predictive power for self-rated health and instrumental activities of daily living (IADL) dependency. RESULTS: Mean age was 97.7 (standard deviation 2.3) years, with a range from 95 to 108, and 74.2% were female. Overall, 16% of our participants were nonfrail, 59% were prefrail, and 25% were frail. Frailty according to FI-32 significantly predicted self-rated health and IADL dependency beyond the effect of age and gender. Inclusion of the new CMF into the regression models provided significant additional predictive power beyond FI-32 on self-rated health, but not IADL dependency. CONCLUSIONS: A CMF should ideally be a multidimensional and multidisciplinary construct including physical, cognitive, functional, psychosocial/family, environmental, and economic factors. |
Persistent Identifier | http://hdl.handle.net/10722/209373 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Kwan, SKJ | en_US |
dc.contributor.author | LAU, HP | en_US |
dc.contributor.author | Cheung, KSL | en_US |
dc.date.accessioned | 2015-04-17T05:11:42Z | - |
dc.date.available | 2015-04-17T05:11:42Z | - |
dc.date.issued | 2015 | en_US |
dc.identifier.citation | Journal of the American Medical Directors Association, 2015, v. 16 n. 6, p. 536.e1-536.e7 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/209373 | - |
dc.description.abstract | OBJECTIVES: A better understanding of the essential components of frailty is important for future developments of management strategies. We aimed to assess the incremental validity of a Comprehensive Model of Frailty (CMF) over Frailty Index (FI) in predicting self-rated health and functional dependency amongst near-centenarians and centenarians. DESIGN: Cross-sectional, community-based study. SETTING: Two community-based social and clinical networks. PARTICIPANTS: One hundred twenty-four community-dwelling Chinese near-centenarians and centenarians. MEASUREMENTS: Frailty was first assessed using a 32-item FI (FI-32). Then, a new CMF was constructed by adding 12 items in the psychological, social/family, environmental, and economic domains to the FI-32. Hierarchical multiple regressions explored whether the new CMF provided significant additional predictive power for self-rated health and instrumental activities of daily living (IADL) dependency. RESULTS: Mean age was 97.7 (standard deviation 2.3) years, with a range from 95 to 108, and 74.2% were female. Overall, 16% of our participants were nonfrail, 59% were prefrail, and 25% were frail. Frailty according to FI-32 significantly predicted self-rated health and IADL dependency beyond the effect of age and gender. Inclusion of the new CMF into the regression models provided significant additional predictive power beyond FI-32 on self-rated health, but not IADL dependency. CONCLUSIONS: A CMF should ideally be a multidimensional and multidisciplinary construct including physical, cognitive, functional, psychosocial/family, environmental, and economic factors. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Journal of the American Medical Directors Association | en_US |
dc.subject | Aging | - |
dc.subject | Centenarians | - |
dc.subject | Frailty | - |
dc.subject | Multidisciplinary | - |
dc.subject | Psychosocial | - |
dc.title | Toward a Comprehensive Model of Frailty: An Emerging Concept From the Hong Kong Centenarian Study | en_US |
dc.type | Article | en_US |
dc.identifier.email | Kwan, SKJ: jskkwan@hku.hk | en_US |
dc.identifier.email | Cheung, KSL: cslk@hku.hk | en_US |
dc.identifier.authority | Kwan, SKJ=rp01868 | en_US |
dc.identifier.authority | Cheung, KSL=rp00615 | en_US |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.jamda.2015.03.005 | en_US |
dc.identifier.scopus | eid_2-s2.0-84929951367 | - |
dc.identifier.hkuros | 242970 | en_US |
dc.identifier.volume | 16 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 536.e1 | - |
dc.identifier.epage | 536.e7 | - |
dc.identifier.isi | WOS:000355134100022 | - |