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Conference Paper: Development of automated patch clamp system for electrophysiology

TitleDevelopment of automated patch clamp system for electrophysiology
Authors
Yang, RunhuaiLai, King W CXi, NingYang, Jie
Issue Date2013
Citation
2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013, 2013, p. 2185-2190 How to Cite?
DOI: http://dx.doi.org/10.1109/ROBIO.2013.6739793
AbstractIn this paper, the development of an automated patch clamp system for cellular electrical information is reported. The system involves several developments that enable the following tasks: 'pipette and cell localization', 'pipette engaging', 'gigaseal', and 'break-in'. The system enables us to engage the glass micro pipette automatically on the cell membrane, and perform whole cell recording on adherent cells. In a patch clamp experiment, the dynamic changes of resistance of the pipette were monitored, and a successful whole cell recording of a cell was demonstrated. © 2013 IEEE.
Persistent Identifierhttp://hdl.handle.net/10722/213398

 

DC FieldValueLanguage
dc.contributor.authorYang, Runhuai-
dc.contributor.authorLai, King W C-
dc.contributor.authorXi, Ning-
dc.contributor.authorYang, Jie-
dc.date.accessioned2015-07-28T04:07:09Z-
dc.date.available2015-07-28T04:07:09Z-
dc.date.issued2013-
dc.identifier.citation2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013, 2013, p. 2185-2190-
dc.identifier.urihttp://hdl.handle.net/10722/213398-
dc.description.abstractIn this paper, the development of an automated patch clamp system for cellular electrical information is reported. The system involves several developments that enable the following tasks: 'pipette and cell localization', 'pipette engaging', 'gigaseal', and 'break-in'. The system enables us to engage the glass micro pipette automatically on the cell membrane, and perform whole cell recording on adherent cells. In a patch clamp experiment, the dynamic changes of resistance of the pipette were monitored, and a successful whole cell recording of a cell was demonstrated. © 2013 IEEE.-
dc.languageeng-
dc.relation.ispartof2013 IEEE International Conference on Robotics and Biomimetics, ROBIO 2013-
dc.titleDevelopment of automated patch clamp system for electrophysiology-
dc.typeConference_Paper-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1109/ROBIO.2013.6739793-
dc.identifier.scopuseid_2-s2.0-84898806707-
dc.identifier.spage2185-
dc.identifier.epage2190-

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