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Conference Paper: Post-ischaemic treatment with melatonin and calpeptin exerts neuroprotective effects against ischaemia/reperfusion injury in a rat model of focal cerebral ischaemia
| Title | Post-ischaemic treatment with melatonin and calpeptin exerts neuroprotective effects against ischaemia/reperfusion injury in a rat model of focal cerebral ischaemia |
|---|---|
| Authors | |
| Keywords | Medical sciences |
| Issue Date | 2015 |
| Publisher | Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk |
| Citation | The 20th Medical Research Conference, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, 17 January 2015. In Hong Kong Medical Journal, 2015, v. 21 suppl. 1, p. 20, abstract no. 21 How to Cite? |
| Abstract | INTRODUCTION: Melatonin is a potent antioxidant. Previously, we have demonstrated beneficial effects of pretreatment with melatonin in rodent models of focal cerebral ischaemia. Cerebral ischaemia increases intracellular concentration of calcium ion and activates several calcium-dependent proteases such as calpain. Calpeptin is a novel calpain inhibitor. The aim of this study was to investigate the neuroprotective role of postischaemia … |
| Persistent Identifier | http://hdl.handle.net/10722/213646 |
| ISSN | 2021 Impact Factor: 1.256 2020 SCImago Journal Rankings: 0.357 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Feng, Y | - |
| dc.contributor.author | Cheung, RTF | - |
| dc.date.accessioned | 2015-08-11T01:52:17Z | - |
| dc.date.available | 2015-08-11T01:52:17Z | - |
| dc.date.issued | 2015 | - |
| dc.identifier.citation | The 20th Medical Research Conference, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, 17 January 2015. In Hong Kong Medical Journal, 2015, v. 21 suppl. 1, p. 20, abstract no. 21 | - |
| dc.identifier.issn | 1024-2708 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/213646 | - |
| dc.description.abstract | INTRODUCTION: Melatonin is a potent antioxidant. Previously, we have demonstrated beneficial effects of pretreatment with melatonin in rodent models of focal cerebral ischaemia. Cerebral ischaemia increases intracellular concentration of calcium ion and activates several calcium-dependent proteases such as calpain. Calpeptin is a novel calpain inhibitor. The aim of this study was to investigate the neuroprotective role of postischaemia … | - |
| dc.language | eng | - |
| dc.publisher | Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk | - |
| dc.relation.ispartof | Hong Kong Medical Journal | - |
| dc.rights | Hong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press. | - |
| dc.subject | Medical sciences | - |
| dc.title | Post-ischaemic treatment with melatonin and calpeptin exerts neuroprotective effects against ischaemia/reperfusion injury in a rat model of focal cerebral ischaemia | - |
| dc.type | Conference_Paper | - |
| dc.identifier.email | Cheung, RTF: rtcheung@hkucc.hku.hk | - |
| dc.identifier.authority | Cheung, RTF=rp00434 | - |
| dc.identifier.hkuros | 248078 | - |
| dc.identifier.volume | 21 | - |
| dc.identifier.issue | suppl. 1 | - |
| dc.identifier.spage | 20, abstract no. 21 | - |
| dc.identifier.epage | 20, abstract no. 21 | - |
| dc.publisher.place | Hong Kong | - |
| dc.identifier.issnl | 1024-2708 | - |