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Conference Paper: The centrosomal protein, TAX1 binding protein 2 (TAX1BP2) regulates the chemo-sensitivity of liver cancer cells

TitleThe centrosomal protein, TAX1 binding protein 2 (TAX1BP2) regulates the chemo-sensitivity of liver cancer cells
Authors
Ching, YPLai, WL
Issue Date2015
PublisherWIN 2015 Symposium.
Citation
The 7th WIN Symposium, Paris, France, 29-30 June 2015. How to Cite?
AbstractBACKGROUND: The centrosomal protein, TAX1 binding protein 2 (TAX1BP2) was first identified as a cellular interacting partner of HTLV-I virus oncoprotein, TAX1. Further investigation has shown that TAX1BP2 was targeted by TAX1 to induce supernumerary centrosome in TAX1-expressing cells. Recently, TAX1BP2 was found to be frequently underexpressed in hepatocellular carcinoma (HCC) and underexpression of TAX1BP2 suppressed the activation of tumor suppressor p53 in a p38 MAPK dependent manner, suggesting that TAX1BP2 is a putative tumor suppressor in HCC. Here we provide ...
DescriptionPoster Session 6 - New Drug Targets: no. P6.04
Persistent Identifierhttp://hdl.handle.net/10722/213792

 

DC FieldValueLanguage
dc.contributor.authorChing, YP-
dc.contributor.authorLai, WL-
dc.date.accessioned2015-08-18T04:56:37Z-
dc.date.available2015-08-18T04:56:37Z-
dc.date.issued2015-
dc.identifier.citationThe 7th WIN Symposium, Paris, France, 29-30 June 2015.-
dc.identifier.urihttp://hdl.handle.net/10722/213792-
dc.descriptionPoster Session 6 - New Drug Targets: no. P6.04-
dc.description.abstractBACKGROUND: The centrosomal protein, TAX1 binding protein 2 (TAX1BP2) was first identified as a cellular interacting partner of HTLV-I virus oncoprotein, TAX1. Further investigation has shown that TAX1BP2 was targeted by TAX1 to induce supernumerary centrosome in TAX1-expressing cells. Recently, TAX1BP2 was found to be frequently underexpressed in hepatocellular carcinoma (HCC) and underexpression of TAX1BP2 suppressed the activation of tumor suppressor p53 in a p38 MAPK dependent manner, suggesting that TAX1BP2 is a putative tumor suppressor in HCC. Here we provide ...-
dc.languageeng-
dc.publisherWIN 2015 Symposium.-
dc.relation.ispartof7th WIN Symposium-
dc.titleThe centrosomal protein, TAX1 binding protein 2 (TAX1BP2) regulates the chemo-sensitivity of liver cancer cells-
dc.typeConference_Paper-
dc.identifier.emailChing, YP: ypching@hku.hk-
dc.identifier.emailLai, WL: bennywll@hku.hk-
dc.identifier.authorityChing, YP=rp00469-
dc.description.naturepublished_or_final_version-
dc.identifier.hkuros246435-
dc.publisher.placeFrance-

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