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Conference Paper: Nanofibrous bicomponent scaffolds for the dual delivery of NGF and GDNF: controlled release of growth factors and their biological effects
Title | Nanofibrous bicomponent scaffolds for the dual delivery of NGF and GDNF: controlled release of growth factors and their biological effects |
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Authors | |
Issue Date | 2015 |
Publisher | Society for Biomaterials. |
Citation | The 2015 Annual Meeting and Exposition of the Society For Biomaterials (SFB 2015), Charlotte, NC., 15-18 April 2015. In Conference Proceedings, 2015, 1pp. How to Cite? |
Abstract | INTRODUCTION: Repairing severely injured peripheral nerves requires suitable devices for bridging the gap and guiding axon growth. Due to limited availability and donor site function loss for autografts, tissue engineeringbased therapy using nerve guide conduits is a promising alternative and hence scaffolds with desired physical, chemical and biological properties are needed. Electrospun nanofibrous scaffolds offer distinctive advantages in facilitating Schwann cell migration and neurite outgrowth [Wang HB, et al., Acta Biomaterialia, 2010, 6:2970-78]. Nerve tissue regeneration can be enhanced by the local delivery of biological cues including nerve growth factor (NGF) and glial cell linederived growth factor (GDNF). Therefore, nanofibrous bicomponent scaffolds were electrospun for the controlled release of NGF and GDNF [Liu C, Wang M, MRS Fall Meeting, Boston, MA, 2013]. In this study, the dual delivery of NGF and GDNF from novel bicomponent ... |
Description | Meeting Theme: Driving Biomaterial Innovation and the Race to Translation |
Persistent Identifier | http://hdl.handle.net/10722/217453 |
ISBN |
DC Field | Value | Language |
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dc.contributor.author | Liu, C | - |
dc.contributor.author | Wang, M | - |
dc.date.accessioned | 2015-09-18T05:59:47Z | - |
dc.date.available | 2015-09-18T05:59:47Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | The 2015 Annual Meeting and Exposition of the Society For Biomaterials (SFB 2015), Charlotte, NC., 15-18 April 2015. In Conference Proceedings, 2015, 1pp. | - |
dc.identifier.isbn | 9781510801066 | - |
dc.identifier.uri | http://hdl.handle.net/10722/217453 | - |
dc.description | Meeting Theme: Driving Biomaterial Innovation and the Race to Translation | - |
dc.description.abstract | INTRODUCTION: Repairing severely injured peripheral nerves requires suitable devices for bridging the gap and guiding axon growth. Due to limited availability and donor site function loss for autografts, tissue engineeringbased therapy using nerve guide conduits is a promising alternative and hence scaffolds with desired physical, chemical and biological properties are needed. Electrospun nanofibrous scaffolds offer distinctive advantages in facilitating Schwann cell migration and neurite outgrowth [Wang HB, et al., Acta Biomaterialia, 2010, 6:2970-78]. Nerve tissue regeneration can be enhanced by the local delivery of biological cues including nerve growth factor (NGF) and glial cell linederived growth factor (GDNF). Therefore, nanofibrous bicomponent scaffolds were electrospun for the controlled release of NGF and GDNF [Liu C, Wang M, MRS Fall Meeting, Boston, MA, 2013]. In this study, the dual delivery of NGF and GDNF from novel bicomponent ... | - |
dc.language | eng | - |
dc.publisher | Society for Biomaterials. | - |
dc.relation.ispartof | Society For Biomaterials Annual Meeting and Exposition. 39th 2015. Transactions of the 39th Annual Meeting Driving Biomaterial Innovation and the Race to Translation | - |
dc.title | Nanofibrous bicomponent scaffolds for the dual delivery of NGF and GDNF: controlled release of growth factors and their biological effects | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Wang, M: memwang@hku.hk | - |
dc.identifier.authority | Wang, M=rp00185 | - |
dc.description.nature | postprint | - |
dc.identifier.hkuros | 251707 | - |
dc.publisher.place | United States | - |