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Conference Paper: Interplay of transforming growth factor beta 1 and endothelin 1 signaling in subchondral osteoblast dysfunction in osteoarthritis

TitleInterplay of transforming growth factor beta 1 and endothelin 1 signaling in subchondral osteoblast dysfunction in osteoarthritis
Authors
Tang, WCWen, CYan, CHChiu, KY
Issue Date2014
Citation
The 34th Annual Meeting of the Hong Kong Orthopaedic Association (HKOA 2014), Hong Kong, 15-16 November 2014, p. 117 How to Cite?
AbstractBACKGROUND: Osteoarthritis (OA) is a common degenerative disease among elderly with some cases associated with hypertension. Endothelin-1 (ET-1) is a hypertension agonist which has been shown to induce type I collagen secretion and inhibit mineralisation in osteoblasts. Upregulation of transforming growth factor beta 1 (TGFβ-1) is associated with the onset of OA. Crosstalks between TGFβ-1 and ET-1 may increase the OA ...
DescriptionElectronic Poster Presentations: P40
Persistent Identifierhttp://hdl.handle.net/10722/217579

 

DC FieldValueLanguage
dc.contributor.authorTang, WC-
dc.contributor.authorWen, C-
dc.contributor.authorYan, CH-
dc.contributor.authorChiu, KY-
dc.date.accessioned2015-09-18T06:05:30Z-
dc.date.available2015-09-18T06:05:30Z-
dc.date.issued2014-
dc.identifier.citationThe 34th Annual Meeting of the Hong Kong Orthopaedic Association (HKOA 2014), Hong Kong, 15-16 November 2014, p. 117-
dc.identifier.urihttp://hdl.handle.net/10722/217579-
dc.descriptionElectronic Poster Presentations: P40-
dc.description.abstractBACKGROUND: Osteoarthritis (OA) is a common degenerative disease among elderly with some cases associated with hypertension. Endothelin-1 (ET-1) is a hypertension agonist which has been shown to induce type I collagen secretion and inhibit mineralisation in osteoblasts. Upregulation of transforming growth factor beta 1 (TGFβ-1) is associated with the onset of OA. Crosstalks between TGFβ-1 and ET-1 may increase the OA ...-
dc.languageeng-
dc.relation.ispartofAnnual Meeting of the Hong Kong Orthopaedic Association, HKOA 2014-
dc.titleInterplay of transforming growth factor beta 1 and endothelin 1 signaling in subchondral osteoblast dysfunction in osteoarthritis-
dc.typeConference_Paper-
dc.identifier.emailWen, C: paulwen@hku.hk-
dc.identifier.emailYan, CH: yanchoi@hku.hk-
dc.identifier.emailChiu, KY: pkychiu@hkucc.hku.hk-
dc.identifier.authorityYan, CH=rp00303-
dc.identifier.authorityChiu, KY=rp00379-
dc.description.naturepostprint-
dc.identifier.hkuros251975-
dc.identifier.spage117-
dc.identifier.epage117-

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