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Conference Paper: Identification of cisplatin-resistance related genes in ovarian clear cell carcinoma using 3D cell culture system
| Title | Identification of cisplatin-resistance related genes in ovarian clear cell carcinoma using 3D cell culture system |
|---|---|
| Authors | |
| Issue Date | 2015 |
| Publisher | European Cancer Organisation (ECCO). |
| Citation | The 2015 EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance, Florence, Italy, 20-23 June 2015. In Conference Proceedings, 2015, p. 91, abstract no. 276 How to Cite? |
| Abstract | INTRODUCTION: Ovarian clear cell carcinoma (OCCC) is well known for its higher prevalence in Asian women and poorer prognosis as compared with other histotypes of epithelial ovarian cancer (EOC) due to higher rate of resistance to platinum based chemotherapy. However, the underlying mechanism has not been fully understood. Three-dimensional (3D) cell culture system with extracellular matrix components mimics the in vivo microenvironment and provides more accurate drug responses than two-dimensional (2D) monolayer cell culture. In this study, we adopted 3D cell culture system to study drug responses and to identify cisplatin-resistance ... |
| Description | Conference Theme: From Cancer Biology to the Clinic |
| Persistent Identifier | http://hdl.handle.net/10722/217901 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Liu, J | - |
| dc.contributor.author | Ngan, HYS | - |
| dc.contributor.author | Chan, DW | - |
| dc.date.accessioned | 2015-09-18T06:17:03Z | - |
| dc.date.available | 2015-09-18T06:17:03Z | - |
| dc.date.issued | 2015 | - |
| dc.identifier.citation | The 2015 EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance, Florence, Italy, 20-23 June 2015. In Conference Proceedings, 2015, p. 91, abstract no. 276 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/217901 | - |
| dc.description | Conference Theme: From Cancer Biology to the Clinic | - |
| dc.description.abstract | INTRODUCTION: Ovarian clear cell carcinoma (OCCC) is well known for its higher prevalence in Asian women and poorer prognosis as compared with other histotypes of epithelial ovarian cancer (EOC) due to higher rate of resistance to platinum based chemotherapy. However, the underlying mechanism has not been fully understood. Three-dimensional (3D) cell culture system with extracellular matrix components mimics the in vivo microenvironment and provides more accurate drug responses than two-dimensional (2D) monolayer cell culture. In this study, we adopted 3D cell culture system to study drug responses and to identify cisplatin-resistance ... | - |
| dc.language | eng | - |
| dc.publisher | European Cancer Organisation (ECCO). | - |
| dc.relation.ispartof | EACR-AACR-SIC Special Conference 2015 | - |
| dc.title | Identification of cisplatin-resistance related genes in ovarian clear cell carcinoma using 3D cell culture system | - |
| dc.type | Conference_Paper | - |
| dc.identifier.email | Ngan, HYS: hysngan@hkucc.hku.hk | - |
| dc.identifier.email | Chan, DW: dwchan@hku.hk | - |
| dc.identifier.authority | Ngan, HYS=rp00346 | - |
| dc.identifier.authority | Chan, DW=rp00543 | - |
| dc.description.nature | postprint | - |
| dc.identifier.hkuros | 251394 | - |
| dc.identifier.spage | 91, abstract no. 276 | - |
| dc.identifier.epage | 91, abstract no. 276 | - |
| dc.publisher.place | Belgium | - |