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Article: A DNA-templated synthesis of encoded small molecules by DNA self-assembly

TitleA DNA-templated synthesis of encoded small molecules by DNA self-assembly
Authors
Cao, CZhao, PLi, ZChen, ZTHuang, YBai, YLi, X
Issue Date2014
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
Citation
Chemical Communications, 2014, v. 50 n. 75, p. 10997-10999 How to Cite?
DOI: http://dx.doi.org/10.1039/C4CC03380A
AbstractWe report a novel method for the synthesis of DNA-encoded libraries without the need for discrete DNA template. Reactant DNAs self-assemble to enable chemical reactions and photo-cleavage transfers the product to the DNA terminus, making it suitable for the subsequent affinity-based selection and hit deconvolution. This journal is © the Partner Organisations 2014.
Persistent Identifierhttp://hdl.handle.net/10722/221116
ISSN
1359-7345
2023 Impact Factor: 4.3
2023 SCImago Journal Rankings: 1.133
ISI Accession Number ID
WOS:000340900400019

 

DC FieldValueLanguage
dc.contributor.authorCao, C-
dc.contributor.authorZhao, P-
dc.contributor.authorLi, Z-
dc.contributor.authorChen, ZT-
dc.contributor.authorHuang, Y-
dc.contributor.authorBai, Y-
dc.contributor.authorLi, X-
dc.date.accessioned2015-10-27T08:39:23Z-
dc.date.available2015-10-27T08:39:23Z-
dc.date.issued2014-
dc.identifier.citationChemical Communications, 2014, v. 50 n. 75, p. 10997-10999-
dc.identifier.issn1359-7345-
dc.identifier.urihttp://hdl.handle.net/10722/221116-
dc.description.abstractWe report a novel method for the synthesis of DNA-encoded libraries without the need for discrete DNA template. Reactant DNAs self-assemble to enable chemical reactions and photo-cleavage transfers the product to the DNA terminus, making it suitable for the subsequent affinity-based selection and hit deconvolution. This journal is © the Partner Organisations 2014.-
dc.languageeng-
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp-
dc.relation.ispartofChemical Communications-
dc.titleA DNA-templated synthesis of encoded small molecules by DNA self-assembly-
dc.typeArticle-
dc.identifier.emailLi, X: xiaoyuli@hku.hk-
dc.identifier.authorityLi, X=rp02080-
dc.identifier.doi10.1039/C4CC03380A-
dc.identifier.pmid25097021-
dc.identifier.scopuseid_2-s2.0-84906545678-
dc.identifier.hkuros284525-
dc.identifier.volume50-
dc.identifier.issue75-
dc.identifier.spage10997-
dc.identifier.epage10999-
dc.identifier.isiWOS:000340900400019-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl1359-7345-

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