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Conference Paper: Rutin increases the efficacy of temozolomide in glioblastoma via autophagy inhibition
Title | Rutin increases the efficacy of temozolomide in glioblastoma via autophagy inhibition |
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Authors | |
Issue Date | 2015 |
Citation | The 2015 Conjoint Annual Scientific Meeting (ASM) of the Hong Kong Neurosurgical Society (HKNS), Hong Kong, 20-21 November 2015. How to Cite? |
Abstract | The chemotherapeutic agent temozolomide (TMZ) is commonly used in glioblastoma (GBM) therapy, but patients usually have a poor prognosis. Rutin, a citrus flavonoid ecglycoside found in edible plants, has neuroprotection and anticancer activities. This study aims to investigate the efficacy of rutin in combination with temozolomide and the underlying mechanisms. In vitro viability assay demonstrated that rutin alone had generally low cytotoxic effect, but it was able to ... |
Description | Conference Theme: Brain Attack: A New Era Posters: no. P-15 |
Persistent Identifier | http://hdl.handle.net/10722/222053 |
DC Field | Value | Language |
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dc.contributor.author | Zhang, P | - |
dc.contributor.author | Leung, GKK | - |
dc.date.accessioned | 2015-12-21T05:54:02Z | - |
dc.date.available | 2015-12-21T05:54:02Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | The 2015 Conjoint Annual Scientific Meeting (ASM) of the Hong Kong Neurosurgical Society (HKNS), Hong Kong, 20-21 November 2015. | - |
dc.identifier.uri | http://hdl.handle.net/10722/222053 | - |
dc.description | Conference Theme: Brain Attack: A New Era | - |
dc.description | Posters: no. P-15 | - |
dc.description.abstract | The chemotherapeutic agent temozolomide (TMZ) is commonly used in glioblastoma (GBM) therapy, but patients usually have a poor prognosis. Rutin, a citrus flavonoid ecglycoside found in edible plants, has neuroprotection and anticancer activities. This study aims to investigate the efficacy of rutin in combination with temozolomide and the underlying mechanisms. In vitro viability assay demonstrated that rutin alone had generally low cytotoxic effect, but it was able to ... | - |
dc.language | eng | - |
dc.relation.ispartof | HKNS Conjoint Annual Scientific Meeting, ASM 2015 | - |
dc.title | Rutin increases the efficacy of temozolomide in glioblastoma via autophagy inhibition | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Zhang, P: pingder@hku.hk | - |
dc.identifier.email | Leung, GKK: gkkleung@hku.hk | - |
dc.identifier.authority | Leung, GKK=rp00522 | - |
dc.description.nature | postprint | - |
dc.identifier.hkuros | 256336 | - |