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Article: Biomimetic mineralization and bioactivity of phosphorylated chitosan
Title | Biomimetic mineralization and bioactivity of phosphorylated chitosan |
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Authors | |
Keywords | Biocompatibility Biomimesis Chitosan (CS) Mineralization Phosphorylated Chitosan |
Issue Date | 2005 |
Publisher | Trans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.net |
Citation | Key Engineering Materials, 2005, v. 288-289, p. 429-432 How to Cite? |
Abstract | Phosphorylated chitosans were synthesized as templates to manipulate hydroxyapatite (HA) crystal nucleation, growth and microstructure. Two kinds of insoluble phosphorylated chitosan were soaked in saturated Ca(OH)2 solution for 4 d and in 1.5× SBF (simulated body fluid) solutions for 14 d at 37 °C for biomimetic mineralization. A lower [P]-content of phosphorylated chitosan promoted greater mineralization than higher [P]-content. Phosphorylated chitosan inhibited osteoblast proliferation and differentiation in vitro, while calcium phosphate phosphorylated chitosan composites did not. |
Persistent Identifier | http://hdl.handle.net/10722/224089 |
ISSN | 2023 SCImago Journal Rankings: 0.172 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chen, ZQ | - |
dc.contributor.author | Li, QL | - |
dc.contributor.author | Zen, Q | - |
dc.contributor.author | Li, Q | - |
dc.contributor.author | Jiang, HB | - |
dc.contributor.author | Liu, LK | - |
dc.contributor.author | Darvell, BW | - |
dc.date.accessioned | 2016-03-23T02:31:09Z | - |
dc.date.available | 2016-03-23T02:31:09Z | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | Key Engineering Materials, 2005, v. 288-289, p. 429-432 | - |
dc.identifier.issn | 1013-9826 | - |
dc.identifier.uri | http://hdl.handle.net/10722/224089 | - |
dc.description.abstract | Phosphorylated chitosans were synthesized as templates to manipulate hydroxyapatite (HA) crystal nucleation, growth and microstructure. Two kinds of insoluble phosphorylated chitosan were soaked in saturated Ca(OH)2 solution for 4 d and in 1.5× SBF (simulated body fluid) solutions for 14 d at 37 °C for biomimetic mineralization. A lower [P]-content of phosphorylated chitosan promoted greater mineralization than higher [P]-content. Phosphorylated chitosan inhibited osteoblast proliferation and differentiation in vitro, while calcium phosphate phosphorylated chitosan composites did not. | - |
dc.language | eng | - |
dc.publisher | Trans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.net | - |
dc.relation.ispartof | Key Engineering Materials | - |
dc.subject | Biocompatibility | - |
dc.subject | Biomimesis | - |
dc.subject | Chitosan (CS) | - |
dc.subject | Mineralization | - |
dc.subject | Phosphorylated Chitosan | - |
dc.title | Biomimetic mineralization and bioactivity of phosphorylated chitosan | - |
dc.type | Article | - |
dc.identifier.email | Darvell, BW: hrdubwd@hkucc.hku.hk | - |
dc.identifier.authority | Darvell, BW=rp00007 | - |
dc.identifier.doi | 10.4028/www.scientific.net/KEM.288-289.429 | - |
dc.identifier.hkuros | 97298 | - |
dc.identifier.volume | 288-289 | - |
dc.identifier.spage | 429 | - |
dc.identifier.epage | 432 | - |
dc.identifier.isi | WOS:000230426600105 | - |
dc.publisher.place | Switzerland | - |
dc.identifier.issnl | 1013-9826 | - |