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- Publisher Website: 10.1111/j.1440-1746.1996.tb00331.x
- Scopus: eid_2-s2.0-0029900787
- PMID: 8872778
- WOS: WOS:A1996VE01700015
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Article: Abnormal gastro-oesophageal reflux in Chinese with atypical chest pain
Title | Abnormal gastro-oesophageal reflux in Chinese with atypical chest pain |
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Authors | |
Keywords | Chinese Gastro-oesophageal reflux Heartburn Regurgitation |
Issue Date | 1996 |
Publisher | Wiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH |
Citation | Journal of Gastroenterology and Hepatology, 1996, v. 11 n. 8, p. 775-779 How to Cite? |
Abstract | Although atypical chest pain has been well described in the Western population, its frequency in Chinese is unknown. Over a period of 42 months, we studied 521 Chinese patients with chest pain and identified 108 patients (20.7%) whose pain was not related to cardiac causes, as determined by exercise ECG or cardiac catheterization. Using 24 h ambulatory pH monitoring and baseline oesophageal manometry, 28.7, 19.4 and 5.6% of these patients were found to have abnormal reflux parameters, abnormal manometric findings or both, respectively. There were significantly more patients complaining of chest pain during the study in the gastro-oesophageal reflux disease (GERD) group than in the non-GERD group (16/31 vs 20/77; P< 0.001). The lower oesophageal sphincter pressure was lower in those with abnormal reflex parameters than in those with normal reflux parameters (12.7±5.4 vs 17.8±5.8 mmHg; P< 0.05). There was no significant difference in symptoms, such as heartburn (54.8 vs 42.9%), regurgitation (38.7 vs 35.1%) and dysphagia (19.4 vs 24.7%), among the two groups. Non-specific changes were the most frequent baseline motility pattern. In conclusion, atypical chest pain and gastro-oesophageal reflux disease are not uncommon in Chinese and this deserves special emphasis as the continuation of anti-anginal drugs may aggravate their condition. |
Persistent Identifier | http://hdl.handle.net/10722/225156 |
ISSN | 2023 Impact Factor: 3.7 2023 SCImago Journal Rankings: 1.179 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lau, GKK | - |
dc.contributor.author | Hui, WM | - |
dc.contributor.author | Lau, CP | - |
dc.contributor.author | Hu, WHC | - |
dc.contributor.author | Lai, KC | - |
dc.contributor.author | Lam, SK | - |
dc.date.accessioned | 2016-04-25T06:21:27Z | - |
dc.date.available | 2016-04-25T06:21:27Z | - |
dc.date.issued | 1996 | - |
dc.identifier.citation | Journal of Gastroenterology and Hepatology, 1996, v. 11 n. 8, p. 775-779 | - |
dc.identifier.issn | 0815-9319 | - |
dc.identifier.uri | http://hdl.handle.net/10722/225156 | - |
dc.description.abstract | Although atypical chest pain has been well described in the Western population, its frequency in Chinese is unknown. Over a period of 42 months, we studied 521 Chinese patients with chest pain and identified 108 patients (20.7%) whose pain was not related to cardiac causes, as determined by exercise ECG or cardiac catheterization. Using 24 h ambulatory pH monitoring and baseline oesophageal manometry, 28.7, 19.4 and 5.6% of these patients were found to have abnormal reflux parameters, abnormal manometric findings or both, respectively. There were significantly more patients complaining of chest pain during the study in the gastro-oesophageal reflux disease (GERD) group than in the non-GERD group (16/31 vs 20/77; P< 0.001). The lower oesophageal sphincter pressure was lower in those with abnormal reflex parameters than in those with normal reflux parameters (12.7±5.4 vs 17.8±5.8 mmHg; P< 0.05). There was no significant difference in symptoms, such as heartburn (54.8 vs 42.9%), regurgitation (38.7 vs 35.1%) and dysphagia (19.4 vs 24.7%), among the two groups. Non-specific changes were the most frequent baseline motility pattern. In conclusion, atypical chest pain and gastro-oesophageal reflux disease are not uncommon in Chinese and this deserves special emphasis as the continuation of anti-anginal drugs may aggravate their condition. | - |
dc.language | eng | - |
dc.publisher | Wiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH | - |
dc.relation.ispartof | Journal of Gastroenterology and Hepatology | - |
dc.subject | Chinese | - |
dc.subject | Gastro-oesophageal reflux | - |
dc.subject | Heartburn | - |
dc.subject | Regurgitation | - |
dc.title | Abnormal gastro-oesophageal reflux in Chinese with atypical chest pain | - |
dc.type | Article | - |
dc.identifier.email | Lau, GKK: gkklau@netvigator.com | - |
dc.identifier.email | Hui, WM: hrmehwm@hkucc.hku.hk | - |
dc.identifier.email | Lau, CP: cplau@hku.hk | - |
dc.identifier.email | Lai, KC: kclai@hkucc.hku.hk | - |
dc.identifier.email | Lam, SK: hrmelsk@hkucc.hku.hk | - |
dc.identifier.doi | 10.1111/j.1440-1746.1996.tb00331.x | - |
dc.identifier.pmid | 8872778 | - |
dc.identifier.scopus | eid_2-s2.0-0029900787 | - |
dc.identifier.hkuros | 22978 | - |
dc.identifier.hkuros | 40443 | - |
dc.identifier.volume | 11 | - |
dc.identifier.issue | 8 | - |
dc.identifier.spage | 775 | - |
dc.identifier.epage | 779 | - |
dc.identifier.isi | WOS:A1996VE01700015 | - |
dc.publisher.place | Australia | - |
dc.identifier.issnl | 0815-9319 | - |