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Patent History
- ApplicationPC T/CN2015086745 2015-08-12
- PublicationWO 2016023491 2016-02-18
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Patent: BIOPHOSPHONATE COMPOUNDS AND GAMMA DELTA T CELL-MEDIATED THERAPY FOR TREATING EPSTEIN-BARR VIRUS-ASSOCIATED DISORDERS
| Title | BIOPHOSPHONATE COMPOUNDS AND GAMMA DELTA T CELL-MEDIATED THERAPY FOR TREATING EPSTEIN-BARR VIRUS-ASSOCIATED DISORDERS |
|---|---|
| Priority Date | 2014-08-12 US 12/2036487P |
| Inventors | |
| Issue Date | 2016 |
| Citation | WO Published patent application WO 2016023491. World Intellectual Property Organization (WIPO), PatentScope, 2016 How to Cite? |
| Abstract | Aminobisphosphonate pamidronate (PAM) can control Epstein-Barr virus (EBV) associated disorders in humanized mice through a Vγ9Vδ2-T-cell dependent mechanism. This suggests a strong potential for a therapeutic approach using PAM to boost human Vγ9Vδ2-T-cell immunity against EBV associated disorders, such as the lymphoproliferative disease (LPD),posttransplant lymphoproliferative disorder (PLPD), Hodgkin's disease,Burkitt's lymphoma, and nasopharyngeal carcinoma (NPC). |
| Persistent Identifier | http://hdl.handle.net/10722/225269 |
| References |
| DC Field | Value | Language |
|---|---|---|
| dc.date.accessioned | 2016-05-03T05:10:12Z | - |
| dc.date.available | 2016-05-03T05:10:12Z | - |
| dc.date.issued | 2016 | - |
| dc.identifier.citation | WO Published patent application WO 2016023491. World Intellectual Property Organization (WIPO), PatentScope, 2016 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/225269 | - |
| dc.description.abstract | Aminobisphosphonate pamidronate (PAM) can control Epstein-Barr virus (EBV) associated disorders in humanized mice through a Vγ9Vδ2-T-cell dependent mechanism. This suggests a strong potential for a therapeutic approach using PAM to boost human Vγ9Vδ2-T-cell immunity against EBV associated disorders, such as the lymphoproliferative disease (LPD),posttransplant lymphoproliferative disorder (PLPD), Hodgkin's disease,Burkitt's lymphoma, and nasopharyngeal carcinoma (NPC). | - |
| dc.title | BIOPHOSPHONATE COMPOUNDS AND GAMMA DELTA T CELL-MEDIATED THERAPY FOR TREATING EPSTEIN-BARR VIRUS-ASSOCIATED DISORDERS | - |
| dc.type | Patent | - |
| dc.identifier.authority | TU, WENWEI=rp00416 | - |
| dc.identifier.authority | LIU, YINPING=rp00269 | - |
| dc.description.nature | published_or_final_version | - |
| dc.contributor.inventor | TU, WENWEI | - |
| dc.contributor.inventor | LIU, YINPING | - |
| dc.contributor.inventor | XIANG, ZHENG | - |
| patents.identifier.application | PC T/CN2015086745 | - |
| patents.description.assignee | UNIV HONG KONG [CN] | - |
| patents.description.country | World Intellectual Property Organization (WIPO) | - |
| patents.date.publication | 2016-02-18 | - |
| dc.relation.references | CN 101926778 (A) 2010-12-29 | - |
| dc.relation.references | XP 002588966 | - |
| patents.identifier.hkutechid | PAED-2014-00536-2 | - |
| patents.date.application | 2015-08-12 | - |
| patents.date.priority | 2014-08-12 US 12/2036487P | - |
| patents.description.cc | wo | - |
| patents.identifier.publication | WO 2016023491 | - |
| patents.relation.family | US 2016045521 (A1) 2016-02-18 | - |
| patents.description.kind | A1 | - |