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- Publisher Website: 10.1016/j.sleep.2009.06.008
- Scopus: eid_2-s2.0-73149100109
- PMID: 19945912
- WOS: WOS:000274321000010
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Article: Validation of a new REM sleep behavior disorder questionnaire (RBDQ-HK)
Title | Validation of a new REM sleep behavior disorder questionnaire (RBDQ-HK) |
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Authors | |
Keywords | Diagnosis Questionnaire Reliability REM sleep behavior disorder (RBD) Symptom severity Validity |
Issue Date | 2010 |
Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/sleep |
Citation | Sleep Medicine, 2010, v. 11 n. 1, p. 43-48 How to Cite? |
Abstract | OBJECTIVES:
There are limited screening instruments for diagnosis of REM sleep behavior disorder (RBD) and none for quantifying the severity of disease. We aimed to validate a 13-item self-reported RBD questionnaire (RBDQ-HK) for diagnostic and monitoring purposes.
METHODS:
Based on ICSD-II and our previous clinical and empirical work, the RBDQ-HK questionnaire was designed and administered in patients attending university-affiliated sleep clinic and psychiatric out-patient clinic, and subjects from the general population. ROC curve and exploratory factor analysis were employed to evaluate the scale, which had a score ranging from 0 to 100.
RESULTS:
One hundred and seven RBD patients [mean age 62.6 (15.5) years; male 70.1%] and 107 control subjects [mean age 55.3 (9.0) years, male 57.9%] completed the questionnaire. The diagnoses of all the study subjects were independently ascertained by clinical interview and PSG. RBD patients had a significantly higher total RBDQ-HK score [mean (s.d.): 32.1 (16.1), range 3-71] than the control group [9.5 (10.2), range 0-55] (p<0.005). The RBDQ-HK demonstrated robust psychometric properties with moderate sensitivity (82.2%), specificity (86.9%), positive predictive value (PPV; 86.3%), and negative predictive value (NPV; 83.0%), high internal consistency and test-retest reliability. Exploratory factor analysis revealed two components (dream-related and behavioral factors) that corresponded to the essential clinical features of RBD. The best cut-off for total score (range 0-100) was at 18/19 and the best cut-off for factor 2 (behavioral factors including sleep talking, shouting, limb movements and sleep-related injuries, range 0-70) was at 7/8.
CONCLUSIONS:
The RBDQ-HK has satisfactory validity and reliability as a measure of clinical RBD symptoms and severity. It may serve as an effective tool for diagnosis and evaluation of the disease course to facilitate future clinical and research studies. |
Persistent Identifier | http://hdl.handle.net/10722/225932 |
ISSN | 2023 Impact Factor: 3.8 2023 SCImago Journal Rankings: 1.368 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Li, X | - |
dc.contributor.author | Wing, YK | - |
dc.contributor.author | Lam, SP | - |
dc.contributor.author | Zhang, J | - |
dc.contributor.author | Yu, MW | - |
dc.contributor.author | Ho, CK | - |
dc.contributor.author | Tsoh, J | - |
dc.contributor.author | Mok, V | - |
dc.date.accessioned | 2016-05-25T08:26:56Z | - |
dc.date.available | 2016-05-25T08:26:56Z | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | Sleep Medicine, 2010, v. 11 n. 1, p. 43-48 | - |
dc.identifier.issn | 1389-9457 | - |
dc.identifier.uri | http://hdl.handle.net/10722/225932 | - |
dc.description.abstract | OBJECTIVES: There are limited screening instruments for diagnosis of REM sleep behavior disorder (RBD) and none for quantifying the severity of disease. We aimed to validate a 13-item self-reported RBD questionnaire (RBDQ-HK) for diagnostic and monitoring purposes. METHODS: Based on ICSD-II and our previous clinical and empirical work, the RBDQ-HK questionnaire was designed and administered in patients attending university-affiliated sleep clinic and psychiatric out-patient clinic, and subjects from the general population. ROC curve and exploratory factor analysis were employed to evaluate the scale, which had a score ranging from 0 to 100. RESULTS: One hundred and seven RBD patients [mean age 62.6 (15.5) years; male 70.1%] and 107 control subjects [mean age 55.3 (9.0) years, male 57.9%] completed the questionnaire. The diagnoses of all the study subjects were independently ascertained by clinical interview and PSG. RBD patients had a significantly higher total RBDQ-HK score [mean (s.d.): 32.1 (16.1), range 3-71] than the control group [9.5 (10.2), range 0-55] (p<0.005). The RBDQ-HK demonstrated robust psychometric properties with moderate sensitivity (82.2%), specificity (86.9%), positive predictive value (PPV; 86.3%), and negative predictive value (NPV; 83.0%), high internal consistency and test-retest reliability. Exploratory factor analysis revealed two components (dream-related and behavioral factors) that corresponded to the essential clinical features of RBD. The best cut-off for total score (range 0-100) was at 18/19 and the best cut-off for factor 2 (behavioral factors including sleep talking, shouting, limb movements and sleep-related injuries, range 0-70) was at 7/8. CONCLUSIONS: The RBDQ-HK has satisfactory validity and reliability as a measure of clinical RBD symptoms and severity. It may serve as an effective tool for diagnosis and evaluation of the disease course to facilitate future clinical and research studies. | - |
dc.language | eng | - |
dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/sleep | - |
dc.relation.ispartof | Sleep Medicine | - |
dc.rights | Posting accepted manuscript (postprint): © <year>. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.subject | Diagnosis | - |
dc.subject | Questionnaire | - |
dc.subject | Reliability | - |
dc.subject | REM sleep behavior disorder (RBD) | - |
dc.subject | Symptom severity | - |
dc.subject | Validity | - |
dc.title | Validation of a new REM sleep behavior disorder questionnaire (RBDQ-HK) | - |
dc.type | Article | - |
dc.identifier.email | Li, X: beshirley@gmail.com | - |
dc.identifier.authority | Li, X=rp02114 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.sleep.2009.06.008 | - |
dc.identifier.pmid | 19945912 | - |
dc.identifier.scopus | eid_2-s2.0-73149100109 | - |
dc.identifier.volume | 11 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 43 | - |
dc.identifier.epage | 48 | - |
dc.identifier.isi | WOS:000274321000010 | - |
dc.publisher.place | Netherlands | - |
dc.identifier.issnl | 1389-9457 | - |