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- Publisher Website: 10.1371/journal.pone.0140393
- Scopus: eid_2-s2.0-84948845109
- PMID: 26461491
- WOS: WOS:000362962300089
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Article: Interruption of Electrical Conductivity of Titanium Dental Implants Suggests a Path Towards Elimination Of Corrosion
Title | Interruption of Electrical Conductivity of Titanium Dental Implants Suggests a Path Towards Elimination Of Corrosion |
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Authors | |
Issue Date | 2015 |
Publisher | Public Library of Science. The Journal's web site is located at http://www.plosone.org/home.action |
Citation | PLoS One, 2015, v. 10 n. 10, p. e0140393 How to Cite? |
Abstract | Peri-implantitis is an inflammatory disease that results in the destruction of soft tissue and bone around the implant. Titanium implant corrosion has been attributed to the implant failure and cytotoxic effects to the alveolar bone. We have documented the extent of titanium release into surrounding plaque in patients with and without peri-implantitis. An in vitro model was designed to represent the actual environment of an implant in a patient's mouth. The model uses actual oral microbiota from a volunteer, allows monitoring electrochemical processes generated by biofilms growing on implants and permits control of biocorrosion electrical current. As determined by next generation DNA sequencing, microbial compositions in experiments with the in vitro model were comparable with the compositions found in patients with implants. It was determined that the electrical conductivity of titanium implants was the key factor responsible for the biocorrosion process. The interruption of the biocorrosion current resulted in a 4-5 fold reduction of corrosion. We propose a new design of dental implant that combines titanium in zero oxidation state for osseointegration and strength, interlaid with a nonconductive ceramic. In addition, we propose electrotherapy for manipulation of microbial biofilms and to induce bone healing in peri-implantitis patients. |
Persistent Identifier | http://hdl.handle.net/10722/227856 |
ISSN | 2023 Impact Factor: 2.9 2023 SCImago Journal Rankings: 0.839 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Pozhitkov, AE | - |
dc.contributor.author | Daubert, D | - |
dc.contributor.author | Donimirski, AB | - |
dc.contributor.author | Goodgion, D | - |
dc.contributor.author | Vagin, MY | - |
dc.contributor.author | Leroux, BG | - |
dc.contributor.author | Hunter, CM | - |
dc.contributor.author | Flemmig, TF | - |
dc.contributor.author | Noble, PA | - |
dc.contributor.author | Bryers, JD | - |
dc.date.accessioned | 2016-07-20T06:45:49Z | - |
dc.date.available | 2016-07-20T06:45:49Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | PLoS One, 2015, v. 10 n. 10, p. e0140393 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | http://hdl.handle.net/10722/227856 | - |
dc.description.abstract | Peri-implantitis is an inflammatory disease that results in the destruction of soft tissue and bone around the implant. Titanium implant corrosion has been attributed to the implant failure and cytotoxic effects to the alveolar bone. We have documented the extent of titanium release into surrounding plaque in patients with and without peri-implantitis. An in vitro model was designed to represent the actual environment of an implant in a patient's mouth. The model uses actual oral microbiota from a volunteer, allows monitoring electrochemical processes generated by biofilms growing on implants and permits control of biocorrosion electrical current. As determined by next generation DNA sequencing, microbial compositions in experiments with the in vitro model were comparable with the compositions found in patients with implants. It was determined that the electrical conductivity of titanium implants was the key factor responsible for the biocorrosion process. The interruption of the biocorrosion current resulted in a 4-5 fold reduction of corrosion. We propose a new design of dental implant that combines titanium in zero oxidation state for osseointegration and strength, interlaid with a nonconductive ceramic. In addition, we propose electrotherapy for manipulation of microbial biofilms and to induce bone healing in peri-implantitis patients. | - |
dc.language | eng | - |
dc.publisher | Public Library of Science. The Journal's web site is located at http://www.plosone.org/home.action | - |
dc.relation.ispartof | PLoS ONE | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.title | Interruption of Electrical Conductivity of Titanium Dental Implants Suggests a Path Towards Elimination Of Corrosion | - |
dc.type | Article | - |
dc.identifier.email | Flemmig, TF: flemmig@hku.hk | - |
dc.identifier.authority | Flemmig, TF=rp01926 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1371/journal.pone.0140393 | - |
dc.identifier.pmid | 26461491 | - |
dc.identifier.scopus | eid_2-s2.0-84948845109 | - |
dc.identifier.hkuros | 269229 | - |
dc.identifier.volume | 10 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | e0140393 | - |
dc.identifier.epage | e0140393 | - |
dc.identifier.isi | WOS:000362962300089 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1932-6203 | - |