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Conference Paper: Concentration-dependent vascular effects of divalent manganese
| Title | Concentration-dependent vascular effects of divalent manganese |
|---|---|
| Authors | |
| Issue Date | 2015 |
| Publisher | Medcom Limited. The Journal's web site is located at http://www.hkcchk.com/journals.php#3 |
| Citation | The 19th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine held in conjunction with the 10th Across the Strait Scientific Conference on Cardiovascular Science, Hong Kong, 21 November 2015. In Journal of the Hong Kong College of Cardiology, 2015, v. 23 n. 2, p. 92, abstract no. OP9 How to Cite? |
| Abstract | OBJECTIVES: Divalent manganese is a cofactor for soluble guanylyl cyclase (sGC), the enzyme producing cyclic GMP in vascular smooth muscle cells that causes relaxation. Manganese competes with magnesium to activate sGC. These divalent cations can bias the activity of the enzyme to produce cyclic nucleotides other than cyclic GMP, in particular cyclic AMP and cyclic IMP. Cyclic IMP, preferably produced in the presence of magnesium, can cause contraction in ... |
| Description | Oral Presentation: no. OP9 |
| Persistent Identifier | http://hdl.handle.net/10722/229985 |
| ISSN | 2023 SCImago Journal Rankings: 0.115 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Detremmerie, CMS | - |
| dc.contributor.author | Leung, SWS | - |
| dc.contributor.author | Vanhoutte, PM | - |
| dc.date.accessioned | 2016-08-23T14:14:28Z | - |
| dc.date.available | 2016-08-23T14:14:28Z | - |
| dc.date.issued | 2015 | - |
| dc.identifier.citation | The 19th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine held in conjunction with the 10th Across the Strait Scientific Conference on Cardiovascular Science, Hong Kong, 21 November 2015. In Journal of the Hong Kong College of Cardiology, 2015, v. 23 n. 2, p. 92, abstract no. OP9 | - |
| dc.identifier.issn | 1027-7811 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/229985 | - |
| dc.description | Oral Presentation: no. OP9 | - |
| dc.description.abstract | OBJECTIVES: Divalent manganese is a cofactor for soluble guanylyl cyclase (sGC), the enzyme producing cyclic GMP in vascular smooth muscle cells that causes relaxation. Manganese competes with magnesium to activate sGC. These divalent cations can bias the activity of the enzyme to produce cyclic nucleotides other than cyclic GMP, in particular cyclic AMP and cyclic IMP. Cyclic IMP, preferably produced in the presence of magnesium, can cause contraction in ... | - |
| dc.language | eng | - |
| dc.publisher | Medcom Limited. The Journal's web site is located at http://www.hkcchk.com/journals.php#3 | - |
| dc.relation.ispartof | Journal of the Hong Kong College of Cardiology | - |
| dc.title | Concentration-dependent vascular effects of divalent manganese | - |
| dc.type | Conference_Paper | - |
| dc.identifier.email | Leung, SWS: swsleung@hku.hk | - |
| dc.identifier.email | Vanhoutte, PM: vanhoutt@hku.hk | - |
| dc.identifier.authority | Leung, SWS=rp00235 | - |
| dc.identifier.authority | Vanhoutte, PM=rp00238 | - |
| dc.description.nature | postprint | - |
| dc.identifier.hkuros | 262190 | - |
| dc.identifier.volume | 23 | - |
| dc.identifier.issue | 2 | - |
| dc.identifier.spage | 92, abstract no. OP9 | - |
| dc.identifier.epage | 92, abstract no. OP9 | - |
| dc.publisher.place | Hong Kong | - |
| dc.identifier.issnl | 1027-7811 | - |