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Article: Comparison between radiographic (2-dimensional and 3-dimensional) and histologic findings of periapical lesions treated with apical surgery

TitleComparison between radiographic (2-dimensional and 3-dimensional) and histologic findings of periapical lesions treated with apical surgery
Authors
Keywordsperiapical radiography
granuloma
periapical lesion
Apical surgery
cone-beam computed tomographic imaging
cyst
Issue Date2015
Citation
Journal of Endodontics, 2015, v. 41, n. 6, p. 804-811 How to Cite?
Abstract© 2015 American Association of Endodontists.Introduction The aim of this study was to evaluate the concordance of 2- and 3-dimensional radiography and histopathology in the diagnosis of periapical lesions. Methods Patients were consecutively enrolled in this study provided that preoperative periapical radiography (PR) and cone-beam computed tomographic imaging of the tooth to be treated with apical surgery were performed. The periapical lesional tissue was histologically analyzed by 2 blinded examiners. The final histologic diagnosis was compared with the radiographic assessments of 4 blinded observers. The initial study material included 62 teeth in the same number of patients. Results Four lesions had to be excluded during processing, resulting in a final number of 58 evaluated cases (31 women and 27 men, mean age = 55 years). The final histologic diagnosis of the periapical lesions included 55 granulomas (94.8%) and 3 cysts (5.2%). Histologic analysis of the tissue samples from the apical lesions exhibited an almost perfect agreement between the 2 experienced investigators with an overall agreement of 94.83% (kappa = 0.8011). Radiographic assessment overestimated cysts by 28.4% (cone-beam computed tomographic imaging) and 20.7% (periapical radiography), respectively. Comparing the correlation of the radiographic diagnosis of 4 observers with the final histologic diagnosis, 2-dimensional (kappa = 0.104) and 3-dimensional imaging (kappa = 0.111) provided only minimum agreement. Conclusions To establish a final diagnosis of an apical radiolucency, the tissue specimen should be evaluated histologically and specified as a granuloma (with/without epithelium) or a cyst. Analysis of 2-dimensional and 3-dimensional radiographic images alike results only in a tentative diagnosis that should be confirmed with biopsy.
Persistent Identifierhttp://hdl.handle.net/10722/236244
ISSN
2023 Impact Factor: 3.5
2023 SCImago Journal Rankings: 1.356
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorBornstein, Michael M.-
dc.contributor.authorBingisser, Andreas C.-
dc.contributor.authorReichart, Peter A.-
dc.contributor.authorSendi, Pedram-
dc.contributor.authorBosshardt, Dieter D.-
dc.contributor.authorVon Arx, Thomas-
dc.date.accessioned2016-11-11T07:43:20Z-
dc.date.available2016-11-11T07:43:20Z-
dc.date.issued2015-
dc.identifier.citationJournal of Endodontics, 2015, v. 41, n. 6, p. 804-811-
dc.identifier.issn0099-2399-
dc.identifier.urihttp://hdl.handle.net/10722/236244-
dc.description.abstract© 2015 American Association of Endodontists.Introduction The aim of this study was to evaluate the concordance of 2- and 3-dimensional radiography and histopathology in the diagnosis of periapical lesions. Methods Patients were consecutively enrolled in this study provided that preoperative periapical radiography (PR) and cone-beam computed tomographic imaging of the tooth to be treated with apical surgery were performed. The periapical lesional tissue was histologically analyzed by 2 blinded examiners. The final histologic diagnosis was compared with the radiographic assessments of 4 blinded observers. The initial study material included 62 teeth in the same number of patients. Results Four lesions had to be excluded during processing, resulting in a final number of 58 evaluated cases (31 women and 27 men, mean age = 55 years). The final histologic diagnosis of the periapical lesions included 55 granulomas (94.8%) and 3 cysts (5.2%). Histologic analysis of the tissue samples from the apical lesions exhibited an almost perfect agreement between the 2 experienced investigators with an overall agreement of 94.83% (kappa = 0.8011). Radiographic assessment overestimated cysts by 28.4% (cone-beam computed tomographic imaging) and 20.7% (periapical radiography), respectively. Comparing the correlation of the radiographic diagnosis of 4 observers with the final histologic diagnosis, 2-dimensional (kappa = 0.104) and 3-dimensional imaging (kappa = 0.111) provided only minimum agreement. Conclusions To establish a final diagnosis of an apical radiolucency, the tissue specimen should be evaluated histologically and specified as a granuloma (with/without epithelium) or a cyst. Analysis of 2-dimensional and 3-dimensional radiographic images alike results only in a tentative diagnosis that should be confirmed with biopsy.-
dc.languageeng-
dc.relation.ispartofJournal of Endodontics-
dc.subjectperiapical radiography-
dc.subjectgranuloma-
dc.subjectperiapical lesion-
dc.subjectApical surgery-
dc.subjectcone-beam computed tomographic imaging-
dc.subjectcyst-
dc.titleComparison between radiographic (2-dimensional and 3-dimensional) and histologic findings of periapical lesions treated with apical surgery-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.joen.2015.01.015-
dc.identifier.scopuseid_2-s2.0-84930085161-
dc.identifier.volume41-
dc.identifier.issue6-
dc.identifier.spage804-
dc.identifier.epage811-
dc.identifier.isiWOS:000356117200004-
dc.identifier.issnl0099-2399-

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