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- Publisher Website: 10.1016/j.vaccine.2004.07.040
- Scopus: eid_2-s2.0-11144313110
- PMID: 15620473
- WOS: WOS:000226545400005
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Article: An economic analysis of annual influenza vaccination of children
Title | An economic analysis of annual influenza vaccination of children |
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Authors | |
Keywords | Economics Influenza vaccination Children High risk |
Issue Date | 2005 |
Citation | Vaccine, 2005, v. 23, n. 8, p. 1004-1014 How to Cite? |
Abstract | We used a Monte Carlo mathematical model to calculate the net economic returns (cost-benefit analysis) from annually vaccinating children against influenza. The model included cohorts of 1000 children in three different age groups (6-23 months, 6-59 months, and 5-14 years), with different proportions of children with high risk conditions (100, 10, and 0%). Vaccinating cohorts of 100% high risk children in all three age groups produced median net savings, regardless of cost of vaccination examined (US$ 30-60/dose administered). Median threshold vaccination costs for cohorts containing 10% high risk children were US$ 48, 46, and 45 per dose administered for age groups 6-23 months, 6-59 months, and 5-14 years, respectively (US$/dose administered below these thresholds generate net savings). For all cohorts, for the range of cost per dose administered examined, the 5th percentiles were net costs. The probability of death, though rare, was the most influential distribution in the model. The number of high-risk children that receive influenza vaccine should be maximized to achieve improved health outcomes as well as cost savings. |
Persistent Identifier | http://hdl.handle.net/10722/238038 |
ISSN | 2023 Impact Factor: 4.5 2023 SCImago Journal Rankings: 1.342 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Meltzer, Martin I. | - |
dc.contributor.author | Neuzil, Kathleen M. | - |
dc.contributor.author | Griffin, Marie R. | - |
dc.contributor.author | Fukuda, Keiji | - |
dc.date.accessioned | 2017-02-03T02:12:41Z | - |
dc.date.available | 2017-02-03T02:12:41Z | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | Vaccine, 2005, v. 23, n. 8, p. 1004-1014 | - |
dc.identifier.issn | 0264-410X | - |
dc.identifier.uri | http://hdl.handle.net/10722/238038 | - |
dc.description.abstract | We used a Monte Carlo mathematical model to calculate the net economic returns (cost-benefit analysis) from annually vaccinating children against influenza. The model included cohorts of 1000 children in three different age groups (6-23 months, 6-59 months, and 5-14 years), with different proportions of children with high risk conditions (100, 10, and 0%). Vaccinating cohorts of 100% high risk children in all three age groups produced median net savings, regardless of cost of vaccination examined (US$ 30-60/dose administered). Median threshold vaccination costs for cohorts containing 10% high risk children were US$ 48, 46, and 45 per dose administered for age groups 6-23 months, 6-59 months, and 5-14 years, respectively (US$/dose administered below these thresholds generate net savings). For all cohorts, for the range of cost per dose administered examined, the 5th percentiles were net costs. The probability of death, though rare, was the most influential distribution in the model. The number of high-risk children that receive influenza vaccine should be maximized to achieve improved health outcomes as well as cost savings. | - |
dc.language | eng | - |
dc.relation.ispartof | Vaccine | - |
dc.subject | Economics | - |
dc.subject | Influenza vaccination | - |
dc.subject | Children | - |
dc.subject | High risk | - |
dc.title | An economic analysis of annual influenza vaccination of children | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.vaccine.2004.07.040 | - |
dc.identifier.pmid | 15620473 | - |
dc.identifier.scopus | eid_2-s2.0-11144313110 | - |
dc.identifier.volume | 23 | - |
dc.identifier.issue | 8 | - |
dc.identifier.spage | 1004 | - |
dc.identifier.epage | 1014 | - |
dc.identifier.isi | WOS:000226545400005 | - |
dc.identifier.issnl | 0264-410X | - |