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Conference Paper: Altered hippocampal functional connectivity with PCC in SCI, MCI and AD

TitleAltered hippocampal functional connectivity with PCC in SCI, MCI and AD
Authors
Zhang, HKwan, SKJChiu, PWHui, SKChan, QMak, HKF
Issue Date2017
PublisherInternational Society for Magnetic Resonance in Medicine.
Citation
The 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 22-27 April 2017. In Conference Proceedings, 2017, abstract no. 2360 How to Cite?
AbstractBrain imaging research has elucidated the structural and functional changes at the clinical stages of AD and MCI, however, the characteristics of resting-state functional connectivity of SCI are largely unstudied. Hippocampus is among the first regions targeted by AD pathology. In this study, we employed resting state fMRI to study the connectivity between hippocampus and posterior cingulate cortex in SCI, MCI and AD groups. In the preliminary results, the connectivity between hippocampus and PCC in SCI was found stronger than control and other two neurodegenerative groups which may suggest that compensatory mechanisms providing preserved hippocampal pathway in SCI.
Persistent Identifierhttp://hdl.handle.net/10722/240983

 

DC FieldValueLanguage
dc.contributor.authorZhang, H-
dc.contributor.authorKwan, SKJ-
dc.contributor.authorChiu, PW-
dc.contributor.authorHui, SK-
dc.contributor.authorChan, Q-
dc.contributor.authorMak, HKF-
dc.date.accessioned2017-05-22T09:20:34Z-
dc.date.available2017-05-22T09:20:34Z-
dc.date.issued2017-
dc.identifier.citationThe 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 22-27 April 2017. In Conference Proceedings, 2017, abstract no. 2360-
dc.identifier.urihttp://hdl.handle.net/10722/240983-
dc.description.abstractBrain imaging research has elucidated the structural and functional changes at the clinical stages of AD and MCI, however, the characteristics of resting-state functional connectivity of SCI are largely unstudied. Hippocampus is among the first regions targeted by AD pathology. In this study, we employed resting state fMRI to study the connectivity between hippocampus and posterior cingulate cortex in SCI, MCI and AD groups. In the preliminary results, the connectivity between hippocampus and PCC in SCI was found stronger than control and other two neurodegenerative groups which may suggest that compensatory mechanisms providing preserved hippocampal pathway in SCI.-
dc.languageeng-
dc.publisherInternational Society for Magnetic Resonance in Medicine.-
dc.relation.ispartofISMRM 2017 Annual Meeting & Exhibition Proceedings-
dc.titleAltered hippocampal functional connectivity with PCC in SCI, MCI and AD-
dc.typeConference_Paper-
dc.identifier.emailKwan, SKJ: jskkwan@hku.hk-
dc.identifier.emailChiu, PW: pwcchiu@hku.hk-
dc.identifier.emailHui, SK: edshui@hku.hk-
dc.identifier.emailMak, HKF: makkf@hku.hk-
dc.identifier.authorityKwan, SKJ=rp01868-
dc.identifier.authorityHui, SK=rp01832-
dc.identifier.authorityMak, HKF=rp00533-
dc.identifier.hkuros272199-
dc.publisher.placeUnited States-

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