Influence of Refractive Status on the Higher-Order Aberration Pattern After Small Incision Lenticule Extraction Surgery

Abstract

Purpose: To study the effect of myopia on the pattern change in higher-order aberrations after small incision lenticule extraction. Methods: Sixty eyes of 60 patients were included: low myopia (≤-3.00 D), moderate myopia (-3.00 D to -6.00 D), and high myopia (≥-6.00 D). Total higher-order aberrations (tHOA), vertical coma (C-1 3 ), horizontal coma (C1 3), and spherical aberration (C0 4) were measured preoperatively and at postoperative 3 months. Results: At the end of 3 months, tHOA changed significantly compared with the preoperative values (P < 0.05), except for C1 3 and C0 4 in the low myopia group. The change in C-1 3 , C1 3 , and C0 4 in the moderate group (-0.299, -0.175, and 0.108 μm) was 2.020, 4.861, and 4.696 times higher than the low group (-0.148, -0.036, 0.023 μm) (P = 0.002, 0.001, 0.001), respectively. The value in the high group (-0.331, -0.192, 0.154 μm) was 1.107, 1.097 (P = 0.478, 0.665), and 1.426 times (P = 0.047) higher than the moderate group. The degree of myopia was positively correlated with -C-1 3 (r = 0.447; P < 0.001) and δC1 3 (r = 0.496; P < 0.001), and negatively correlated with δtHOA (r = -0.363, P = 0.004) and -C0 4 (r = -0.599; P < 0.001). Conclusions: The study showed a different pattern of change in ocular aberrations after small incision lenticule extraction in patients with varying degrees of myopia. In patients with low myopia, there was no increase in C1 3 or C0 4 . In high myopia, however, C04 increased with the degree of myopia, whereas the rising rate of coma was slowing. © Copyright 2017 Wolters Kluwer Health, Inc. All rights reserved.