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Article: Prevalence of depressive and anxiety disorders and validation of the Hospital Anxiety and Depression Scale as a screening tool in axial spondyloarthritis patients
Title | Prevalence of depressive and anxiety disorders and validation of the Hospital Anxiety and Depression Scale as a screening tool in axial spondyloarthritis patients |
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Authors | |
Keywords | hospital anxiety and depression scale depressive disorder anxiety disorder spondyloarthritis |
Issue Date | 2017 |
Citation | International Journal of Rheumatic Diseases, 2017, v. 20, n. 3, p. 317-325 How to Cite? |
Abstract | © 2014 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd Objective: To determine the prevalence of anxiety and depression in axial spondyloarthritis (SpA) patients by a psychiatrist using the Chinese-bilingual Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, fourth edition patient research version (CB-SCID-I/P), and to examine the effectiveness of the Hospital Anxiety and Depression Scale (HADS) as a screening tool. Methods: We recruited 160 Chinese axial-SpA patients to determine the prevalence of anxiety and depression using the CB-SCID-I/P. Recruited subjects were asked to complete the HADS. HADS, HADS-depression (HADS-D) subscale and HADS-anxiety (HADS-A) subscale were analyzed to determine their effectiveness in screening for depressive and anxiety disorders. Results: The prevalence of current major depressive disorder (MDD) and anxiety disorder were 10.6% and 15.6%, respectively. The full-scale HADS outperformed the HADS-D subscale in screening for current MDD (area under the curve [AUC] 0.889; 0.844) and all depressive disorders (AUC 0.885; 0.862) while the HADS-A subscale outperformed the full scale HADS in screening for anxiety disorders (AUC 0.894; 0.846). The optimal cut-off point of the full scale HADS for screening current MDD and all depressive disorders were 7/8 and 6/7, yielding a sensitivity of 82.4% and 83.9%, specificity of 78.7% and 74.8%, respectively. The optimal cut-off point of HADS-A subscale for screening anxiety disorders was 6/7, yielding a sensitivity of 88.0% and specificity of 74.4%. Conclusion: The prevalence of MDD and anxiety disorder in SpA patients were 10.6% and 15.6%, respectively. We recommend using the full-scale HADS in screening for depressive disorders and HADS-A subscale for anxiety disorders. |
Persistent Identifier | http://hdl.handle.net/10722/249100 |
ISSN | 2023 Impact Factor: 2.4 2023 SCImago Journal Rankings: 0.653 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chan, Cynthia Y.Y. | - |
dc.contributor.author | Tsang, Helen H.L. | - |
dc.contributor.author | Lau, C. S. | - |
dc.contributor.author | Chung, H. Y. | - |
dc.date.accessioned | 2017-10-27T05:59:06Z | - |
dc.date.available | 2017-10-27T05:59:06Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | International Journal of Rheumatic Diseases, 2017, v. 20, n. 3, p. 317-325 | - |
dc.identifier.issn | 1756-1841 | - |
dc.identifier.uri | http://hdl.handle.net/10722/249100 | - |
dc.description.abstract | © 2014 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd Objective: To determine the prevalence of anxiety and depression in axial spondyloarthritis (SpA) patients by a psychiatrist using the Chinese-bilingual Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, fourth edition patient research version (CB-SCID-I/P), and to examine the effectiveness of the Hospital Anxiety and Depression Scale (HADS) as a screening tool. Methods: We recruited 160 Chinese axial-SpA patients to determine the prevalence of anxiety and depression using the CB-SCID-I/P. Recruited subjects were asked to complete the HADS. HADS, HADS-depression (HADS-D) subscale and HADS-anxiety (HADS-A) subscale were analyzed to determine their effectiveness in screening for depressive and anxiety disorders. Results: The prevalence of current major depressive disorder (MDD) and anxiety disorder were 10.6% and 15.6%, respectively. The full-scale HADS outperformed the HADS-D subscale in screening for current MDD (area under the curve [AUC] 0.889; 0.844) and all depressive disorders (AUC 0.885; 0.862) while the HADS-A subscale outperformed the full scale HADS in screening for anxiety disorders (AUC 0.894; 0.846). The optimal cut-off point of the full scale HADS for screening current MDD and all depressive disorders were 7/8 and 6/7, yielding a sensitivity of 82.4% and 83.9%, specificity of 78.7% and 74.8%, respectively. The optimal cut-off point of HADS-A subscale for screening anxiety disorders was 6/7, yielding a sensitivity of 88.0% and specificity of 74.4%. Conclusion: The prevalence of MDD and anxiety disorder in SpA patients were 10.6% and 15.6%, respectively. We recommend using the full-scale HADS in screening for depressive disorders and HADS-A subscale for anxiety disorders. | - |
dc.language | eng | - |
dc.relation.ispartof | International Journal of Rheumatic Diseases | - |
dc.subject | hospital anxiety and depression scale | - |
dc.subject | depressive disorder | - |
dc.subject | anxiety disorder | - |
dc.subject | spondyloarthritis | - |
dc.title | Prevalence of depressive and anxiety disorders and validation of the Hospital Anxiety and Depression Scale as a screening tool in axial spondyloarthritis patients | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1111/1756-185X.12456 | - |
dc.identifier.scopus | eid_2-s2.0-84910617555 | - |
dc.identifier.hkuros | 253911 | - |
dc.identifier.hkuros | 301852 | - |
dc.identifier.volume | 20 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 317 | - |
dc.identifier.epage | 325 | - |
dc.identifier.eissn | 1756-185X | - |
dc.identifier.isi | WOS:000402829900004 | - |
dc.identifier.issnl | 1756-1841 | - |