File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Hydrogen Breath Testing In East And Southeast Asia

TitleHydrogen Breath Testing In East And Southeast Asia
Authors
KeywordsAsia
breath test
diet
functional dyspepsia
hydrogen
irritable bowel syndrome
Issue Date2018
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.jcge.com
Citation
Journal of Clinical Gastroenterology, 2018, v. 52 n. 3, p. 185-193 How to Cite?
AbstractBreath hydrogen tests are popular, noninvasive tests for the assessment of carbohydrate fermentation in patients with irritable bowel syndrome (IBS) and functional dyspepsia (FD). There is limited information regarding the utility of breath hydrogen and methane tests in IBS and FD patients in East and Southeast Asia. This review aims to summarize current literature about common indications of breath testing in this region, the genesis of functional gastrointestinal symptoms by provocative breath testing and provide suggestions for correct use. The most common testing indication is the assessment of lactose intolerance, followed by small intestinal bacterial overgrowth (SIBO) and differentiation of intestinal gas profiles in research setting. Studies in this region not only documented a high prevalence of lactose malabsorption but a population, both healthy and IBS, that is highly symptomatic to typical lactose intakes. Breath hydrogen assessment of other fermentable carbohydrates (FODMAPs) are fairly uncommon, whereas methane breath testing is almost nonexistent. Cumulative hydrogen production following lactulose was also not excessive in IBS patients compared with controls. The evidence however, for the detection of SIBO suggests limited reliability in the use of lactulose or glucose breath testing alone and inconclusive data on its correlation with symptoms. Conversely, little has been carried out in FD. In conclusion, breath testing should be limited in the predicting patients with SIBO for directing clinical management but can be considered in the objective assessment of lactose malabsorption within a low FODMAP diet. Recommendations to improve the interpretation of breath testing in research were also provided.
Persistent Identifierhttp://hdl.handle.net/10722/249669
ISSN
2023 Impact Factor: 2.8
2023 SCImago Journal Rankings: 0.906
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorYao, CK-
dc.contributor.authorChu, HS-
dc.contributor.authorTan, VPY-
dc.date.accessioned2017-11-21T03:05:22Z-
dc.date.available2017-11-21T03:05:22Z-
dc.date.issued2018-
dc.identifier.citationJournal of Clinical Gastroenterology, 2018, v. 52 n. 3, p. 185-193-
dc.identifier.issn0192-0790-
dc.identifier.urihttp://hdl.handle.net/10722/249669-
dc.description.abstractBreath hydrogen tests are popular, noninvasive tests for the assessment of carbohydrate fermentation in patients with irritable bowel syndrome (IBS) and functional dyspepsia (FD). There is limited information regarding the utility of breath hydrogen and methane tests in IBS and FD patients in East and Southeast Asia. This review aims to summarize current literature about common indications of breath testing in this region, the genesis of functional gastrointestinal symptoms by provocative breath testing and provide suggestions for correct use. The most common testing indication is the assessment of lactose intolerance, followed by small intestinal bacterial overgrowth (SIBO) and differentiation of intestinal gas profiles in research setting. Studies in this region not only documented a high prevalence of lactose malabsorption but a population, both healthy and IBS, that is highly symptomatic to typical lactose intakes. Breath hydrogen assessment of other fermentable carbohydrates (FODMAPs) are fairly uncommon, whereas methane breath testing is almost nonexistent. Cumulative hydrogen production following lactulose was also not excessive in IBS patients compared with controls. The evidence however, for the detection of SIBO suggests limited reliability in the use of lactulose or glucose breath testing alone and inconclusive data on its correlation with symptoms. Conversely, little has been carried out in FD. In conclusion, breath testing should be limited in the predicting patients with SIBO for directing clinical management but can be considered in the objective assessment of lactose malabsorption within a low FODMAP diet. Recommendations to improve the interpretation of breath testing in research were also provided.-
dc.languageeng-
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.jcge.com-
dc.relation.ispartofJournal of Clinical Gastroenterology-
dc.rightsThis is a non-final version of an article published in final form in (provide complete journal citation)-
dc.subjectAsia-
dc.subjectbreath test-
dc.subjectdiet-
dc.subjectfunctional dyspepsia-
dc.subjecthydrogen-
dc.subjectirritable bowel syndrome-
dc.titleHydrogen Breath Testing In East And Southeast Asia-
dc.typeArticle-
dc.identifier.emailYao, CK: chuyao@hku.hk-
dc.identifier.emailTan, VPY: vpytan@hku.hk-
dc.identifier.authorityTan, VPY=rp01458-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/MCG.0000000000000943-
dc.identifier.pmid29035975-
dc.identifier.scopuseid_2-s2.0-85043457587-
dc.identifier.hkuros283302-
dc.identifier.volume52-
dc.identifier.issue3-
dc.identifier.spage185-
dc.identifier.epage193-
dc.identifier.isiWOS:000427034100002-
dc.publisher.placeUnited States-
dc.identifier.issnl0192-0790-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats