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Article: First draft genome sequence of the pathogenic fungus Lomentospora prolificans (formerly Scedosporium prolificans)

TitleFirst draft genome sequence of the pathogenic fungus Lomentospora prolificans (formerly Scedosporium prolificans)
Authors
KeywordsNanopore sequencing
Pathogen genomics
Genome assembly
Fungal genomics
Issue Date2017
Citation
G3: Genes, Genomes, Genetics, 2017, v. 7, n. 11, p. 3831-3836 How to Cite?
Abstract© 2017 Luo et al. Here we describe the sequencing and assembly of the pathogenic fungus Lomentospora prolificans using a combination of short, highly accurate Illumina reads and additional coverage in very long Oxford Nanopore reads. The resulting assembly is highly contiguous, containing a total of 37,627,092 bp with over 98% of the sequence in just 26 scaffolds. Annotation identified 8896 protein-coding genes. Pulsedfield gel analysis suggests that this organism contains at least 7 and possibly 11 chromosomes, the two longest of which have sizes corresponding closely to the sizes of the longest scaffolds, at 6.6 and 5.7 Mb.
Persistent Identifierhttp://hdl.handle.net/10722/250886
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLuo, Ruibang-
dc.contributor.authorZimin, Aleksey-
dc.contributor.authorWorkman, Rachael-
dc.contributor.authorFan, Yunfan-
dc.contributor.authorPertea, Geo-
dc.contributor.authorGrossman, Nina-
dc.contributor.authorWear, Maggie P.-
dc.contributor.authorJia, Bei-
dc.contributor.authorMiller, Heather-
dc.contributor.authorCasadevall, Arturo-
dc.contributor.authorTimp, Winston-
dc.contributor.authorZhang, Sean X.-
dc.contributor.authorSalzberg, Steven L.-
dc.date.accessioned2018-02-01T01:53:59Z-
dc.date.available2018-02-01T01:53:59Z-
dc.date.issued2017-
dc.identifier.citationG3: Genes, Genomes, Genetics, 2017, v. 7, n. 11, p. 3831-3836-
dc.identifier.urihttp://hdl.handle.net/10722/250886-
dc.description.abstract© 2017 Luo et al. Here we describe the sequencing and assembly of the pathogenic fungus Lomentospora prolificans using a combination of short, highly accurate Illumina reads and additional coverage in very long Oxford Nanopore reads. The resulting assembly is highly contiguous, containing a total of 37,627,092 bp with over 98% of the sequence in just 26 scaffolds. Annotation identified 8896 protein-coding genes. Pulsedfield gel analysis suggests that this organism contains at least 7 and possibly 11 chromosomes, the two longest of which have sizes corresponding closely to the sizes of the longest scaffolds, at 6.6 and 5.7 Mb.-
dc.languageeng-
dc.relation.ispartofG3: Genes, Genomes, Genetics-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectNanopore sequencing-
dc.subjectPathogen genomics-
dc.subjectGenome assembly-
dc.subjectFungal genomics-
dc.titleFirst draft genome sequence of the pathogenic fungus Lomentospora prolificans (formerly Scedosporium prolificans)-
dc.typeArticle-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1534/g3.117.300107-
dc.identifier.pmid28963165-
dc.identifier.pmcidPMC5677167-
dc.identifier.scopuseid_2-s2.0-85032977624-
dc.identifier.hkuros310905-
dc.identifier.volume7-
dc.identifier.issue11-
dc.identifier.spage3831-
dc.identifier.epage3836-
dc.identifier.eissn2160-1836-
dc.identifier.isiWOS:000414469000024-
dc.identifier.issnl2160-1836-

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