File Download
There are no files associated with this item.
Supplementary
-
Citations:
- Appears in Collections:
Conference Paper: Influenza viruses in the air: in experimental settings and within live poultry markets
Title | Influenza viruses in the air: in experimental settings and within live poultry markets |
---|---|
Authors | |
Issue Date | 2016 |
Citation | Symposium on Transmission and Control of Respiratory Pathogens, Hong Kong, 14 J2016 How to Cite? |
Abstract | Influenza virus transmits via multiple non-mutually exclusive modes; infections are mediated via virus-laden particles of various sizes that confer fomite, droplet, or airborne transmission. The specific mode of transmission associated with efficient spread of influenza viruses among their adapted hosts are not fully understood. In experimental settings, the application of animal models offer the benefit of controlled prior exposure history while studying influenza transmission. We evaluate the significance of droplet and airborne transmission potential in ferrets by controlling the size of virus-laden particles passed from the inoculated donors to the naïve contacts in the air, as droplet nuclei less than 5 μm mediate airborne transmission. To understand if specific host factors are associated with efficient transmission, early transcriptomic responses from ferret respiratory tissues were compared after inoculation with pandemic H1N1 and swine influenza viruses that differed by the respiratory droplet transmissibility. At the human-animal interface, we assess the quantity, size and viability of influenza virus-laden particles at live poultry markets in Guangzhou city to analyze the potential modes of transmission for zoonotic infections. Dissecting the black box of influenza transmission with collaborative multidisciplinary approach and cutting edge technology will provide valuable insights for developing effective control measures. |
Description | Jointly organized by WHO Collaborating Centre for Infectious Disease Epidemiology and Control at the School of Public Health of the University of Hong Kong and RGC Theme-based Research Scheme on Viral, Host and Environmental Determinants of Influenza Virus Transmission and Pathogenesis Session 5 |
Persistent Identifier | http://hdl.handle.net/10722/255173 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yen, H | - |
dc.date.accessioned | 2018-06-28T08:17:55Z | - |
dc.date.available | 2018-06-28T08:17:55Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Symposium on Transmission and Control of Respiratory Pathogens, Hong Kong, 14 J2016 | - |
dc.identifier.uri | http://hdl.handle.net/10722/255173 | - |
dc.description | Jointly organized by WHO Collaborating Centre for Infectious Disease Epidemiology and Control at the School of Public Health of the University of Hong Kong and RGC Theme-based Research Scheme on Viral, Host and Environmental Determinants of Influenza Virus Transmission and Pathogenesis | - |
dc.description | Session 5 | - |
dc.description.abstract | Influenza virus transmits via multiple non-mutually exclusive modes; infections are mediated via virus-laden particles of various sizes that confer fomite, droplet, or airborne transmission. The specific mode of transmission associated with efficient spread of influenza viruses among their adapted hosts are not fully understood. In experimental settings, the application of animal models offer the benefit of controlled prior exposure history while studying influenza transmission. We evaluate the significance of droplet and airborne transmission potential in ferrets by controlling the size of virus-laden particles passed from the inoculated donors to the naïve contacts in the air, as droplet nuclei less than 5 μm mediate airborne transmission. To understand if specific host factors are associated with efficient transmission, early transcriptomic responses from ferret respiratory tissues were compared after inoculation with pandemic H1N1 and swine influenza viruses that differed by the respiratory droplet transmissibility. At the human-animal interface, we assess the quantity, size and viability of influenza virus-laden particles at live poultry markets in Guangzhou city to analyze the potential modes of transmission for zoonotic infections. Dissecting the black box of influenza transmission with collaborative multidisciplinary approach and cutting edge technology will provide valuable insights for developing effective control measures. | - |
dc.language | eng | - |
dc.relation.ispartof | Symposium on Transmission and Control of Respiratory Pathogens, Hong Kong | - |
dc.title | Influenza viruses in the air: in experimental settings and within live poultry markets | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Yen, H: hyen@hku.hk | - |
dc.identifier.authority | Yen, H=rp00304 | - |
dc.identifier.hkuros | 275758 | - |