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Conference Paper: Rise in creatine kinase in a patient on statin
Title | Rise in creatine kinase in a patient on statin |
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Authors | |
Issue Date | 2018 |
Publisher | The Hong Kong College of Family Physicians. |
Citation | Hong Kong Primary Care Conference 2018: Family Physician – Nexus of the New Era of Primary Care, Hong Kong, 23–24 June 2018. In Programme Book, p. 51 How to Cite? |
Abstract | Introduction: Statins are commonly used in family medicine practice. Myopathy is one of the known possible side effects. Should creatine kinase (CK) be routinely checked for patients on statin? This is a clinical case report. Methods: A 62-years old lady was followed-up in a general outpatient clinic for hypertension, hyperlipidaemia and obesity. Her 10-years cardiovascular risk was medium. A routine blood test of her in June 2017 showed low density lipoprotein cholesterol (LDL_C) 4.1mmol/L. She was put on simvastatin 20mg nocte. The attending doctor ordered a follow-up lipid profile, routine liver function and CK checking 3 months later. Patient had her blood test in Sept 2017. Here LDL_C dropped to 2.7mmol/L. Her liver function was normal but her CK was elevated to 198 U/L (Ref: 40-161U/L). Patient reported no myalgia. However, she recalled having an upper respiratory tract infection treated symptomatically during her blood test. The simvastatin was continued at the same dose. CK was rechecked 1 month later in Oct 2017 and dropped to 177U/L. Patient remained asymptomatic. Simvastatin was continued. Further repeating of CK another month later in Nov 2017 noticed the level almost normalized (169U/L). Results and Discussion: Upon a 3 months’ observation without intervention, the rise in CK didn’t seem to be related to the statin given. This case demonstrated a routine checking of CK in an asymptomatic patient on statin would be unnecessary. This echoes with most of the international guidelines. |
Description | Poster Presentation - no. 004 |
Persistent Identifier | http://hdl.handle.net/10722/261060 |
DC Field | Value | Language |
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dc.contributor.author | Tse, TYE | - |
dc.date.accessioned | 2018-09-14T08:51:49Z | - |
dc.date.available | 2018-09-14T08:51:49Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Hong Kong Primary Care Conference 2018: Family Physician – Nexus of the New Era of Primary Care, Hong Kong, 23–24 June 2018. In Programme Book, p. 51 | - |
dc.identifier.uri | http://hdl.handle.net/10722/261060 | - |
dc.description | Poster Presentation - no. 004 | - |
dc.description.abstract | Introduction: Statins are commonly used in family medicine practice. Myopathy is one of the known possible side effects. Should creatine kinase (CK) be routinely checked for patients on statin? This is a clinical case report. Methods: A 62-years old lady was followed-up in a general outpatient clinic for hypertension, hyperlipidaemia and obesity. Her 10-years cardiovascular risk was medium. A routine blood test of her in June 2017 showed low density lipoprotein cholesterol (LDL_C) 4.1mmol/L. She was put on simvastatin 20mg nocte. The attending doctor ordered a follow-up lipid profile, routine liver function and CK checking 3 months later. Patient had her blood test in Sept 2017. Here LDL_C dropped to 2.7mmol/L. Her liver function was normal but her CK was elevated to 198 U/L (Ref: 40-161U/L). Patient reported no myalgia. However, she recalled having an upper respiratory tract infection treated symptomatically during her blood test. The simvastatin was continued at the same dose. CK was rechecked 1 month later in Oct 2017 and dropped to 177U/L. Patient remained asymptomatic. Simvastatin was continued. Further repeating of CK another month later in Nov 2017 noticed the level almost normalized (169U/L). Results and Discussion: Upon a 3 months’ observation without intervention, the rise in CK didn’t seem to be related to the statin given. This case demonstrated a routine checking of CK in an asymptomatic patient on statin would be unnecessary. This echoes with most of the international guidelines. | - |
dc.language | eng | - |
dc.publisher | The Hong Kong College of Family Physicians. | - |
dc.relation.ispartof | Hong Kong Primary Care Conference 2018 | - |
dc.title | Rise in creatine kinase in a patient on statin | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Tse, TYE: emilyht@hku.hk | - |
dc.identifier.authority | Tse, TYE=rp02382 | - |
dc.identifier.hkuros | 291139 | - |
dc.identifier.spage | 51 | - |
dc.identifier.epage | 51 | - |
dc.publisher.place | Hong Kong | - |