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- Publisher Website: 10.1002/hup.470070207
- Scopus: eid_2-s2.0-0026516183
- WOS: WOS:A1992HT74100006
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Article: The plasma haloperidol and reduced haloperidol concentrations in chinese schizophrenic patients: Relationship between reduced haloperidol/haloperidol ratio and red blood cell haloperidol reductase activity
Title | The plasma haloperidol and reduced haloperidol concentrations in chinese schizophrenic patients: Relationship between reduced haloperidol/haloperidol ratio and red blood cell haloperidol reductase activity |
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Authors | |
Keywords | Haloperidol schizophrenic reduced haloperidol |
Issue Date | 1992 |
Citation | Human Psychopharmacology: Clinical and Experimental, 1992, v. 7, n. 2, p. 123-128 How to Cite? |
Abstract | Fifteen chinese schizophrenic patients were given titrated doses of haloperidol (0.05‐0.42 mg/kg) for two weeks. All these 15 patients were in clinical remission on maintenance dose of haloperidol. The mean plasma haloperidol and reduced haloperidol concentrations were 16.8 ± 4.8 ng/ml and 13.6‐ 5.7 ng/ml respectively. The plasma RHAL/HAL ratio was in the range of 0.13±1.94. These values were similar to that reported for the Japanese population. The frequency distribution appeared to be bimodal. RBC reductase activity were found to be distributed normally and no correlation was found between plasma RHAL/HAL ratio and RBC reductase activity. Copyright © 1992 John Wiley & Sons, Ltd. |
Persistent Identifier | http://hdl.handle.net/10722/264879 |
ISSN | 2023 Impact Factor: 1.8 2023 SCImago Journal Rankings: 0.541 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Wong, B. Y.M. | - |
dc.contributor.author | Chan, Mo‐Yin ‐Y | - |
dc.contributor.author | Wong, M. T.H. | - |
dc.contributor.author | Lieh‐Mak, F. | - |
dc.date.accessioned | 2018-11-08T01:35:10Z | - |
dc.date.available | 2018-11-08T01:35:10Z | - |
dc.date.issued | 1992 | - |
dc.identifier.citation | Human Psychopharmacology: Clinical and Experimental, 1992, v. 7, n. 2, p. 123-128 | - |
dc.identifier.issn | 0885-6222 | - |
dc.identifier.uri | http://hdl.handle.net/10722/264879 | - |
dc.description.abstract | Fifteen chinese schizophrenic patients were given titrated doses of haloperidol (0.05‐0.42 mg/kg) for two weeks. All these 15 patients were in clinical remission on maintenance dose of haloperidol. The mean plasma haloperidol and reduced haloperidol concentrations were 16.8 ± 4.8 ng/ml and 13.6‐ 5.7 ng/ml respectively. The plasma RHAL/HAL ratio was in the range of 0.13±1.94. These values were similar to that reported for the Japanese population. The frequency distribution appeared to be bimodal. RBC reductase activity were found to be distributed normally and no correlation was found between plasma RHAL/HAL ratio and RBC reductase activity. Copyright © 1992 John Wiley & Sons, Ltd. | - |
dc.language | eng | - |
dc.relation.ispartof | Human Psychopharmacology: Clinical and Experimental | - |
dc.subject | Haloperidol | - |
dc.subject | schizophrenic | - |
dc.subject | reduced haloperidol | - |
dc.title | The plasma haloperidol and reduced haloperidol concentrations in chinese schizophrenic patients: Relationship between reduced haloperidol/haloperidol ratio and red blood cell haloperidol reductase activity | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1002/hup.470070207 | - |
dc.identifier.scopus | eid_2-s2.0-0026516183 | - |
dc.identifier.volume | 7 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 123 | - |
dc.identifier.epage | 128 | - |
dc.identifier.eissn | 1099-1077 | - |
dc.identifier.isi | WOS:A1992HT74100006 | - |
dc.identifier.issnl | 0885-6222 | - |