Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1186/s13256-018-1893-7
- Scopus: eid_2-s2.0-85057596090
- PMID: 30509326
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Optic neuritis as the initial clinical presentation of limbic encephalitis: a case report
Title | Optic neuritis as the initial clinical presentation of limbic encephalitis: a case report |
---|---|
Authors | |
Keywords | Optic neuritis Limbic encephalitis Autoimmune encephalitis Paraneoplastic syndrome |
Issue Date | 2018 |
Publisher | BioMed Central Ltd. The Journal's web site is located at http://www.jmedicalcasereports.com/ |
Citation | Journal of Medical Case Reports, 2018, v. 12 n. 1, article no. 357, p. 1-5 How to Cite? |
Abstract | Background: Limbic encephalitis is characterized by rapid onset of working memory deficit, mood changes, and often seizures. The condition has a strong paraneoplastic association, but not all cases are invariably due to tumors. Case presentation: We present a case of limbic encephalitis in a Chinese patient who initially presented to our hospital with optic neuritis and no other neurological symptoms. The diagnosis was made radiologically, and cognitive and neurological symptoms did not occur until 5 months later. Extensive investigations for autoimmune, infective, and neoplastic causes were all negative. A working diagnosis of paraneoplastic neurological syndrome was made, and the patient is being managed with high-dose steroid therapy according to the Optic Neuritis Treatment Trial protocol during relapses, as well as with tumor surveillance. Conclusions: This case highlights ocular symptoms as important clues for diagnosing neurological diseases, as well as autoimmune encephalitis as an important differential diagnosis in the management of “idiopathic” optic neuritis in the Chinese population. |
Persistent Identifier | http://hdl.handle.net/10722/265954 |
ISSN | 2023 Impact Factor: 0.9 2023 SCImago Journal Rankings: 0.304 |
PubMed Central ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cheung, SSL | - |
dc.contributor.author | Lau, GKK | - |
dc.contributor.author | Chan, KH | - |
dc.contributor.author | Wong, YHI | - |
dc.contributor.author | Lai, JSM | - |
dc.contributor.author | Tang, WK | - |
dc.contributor.author | Shih, KC | - |
dc.date.accessioned | 2018-12-17T02:16:21Z | - |
dc.date.available | 2018-12-17T02:16:21Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Journal of Medical Case Reports, 2018, v. 12 n. 1, article no. 357, p. 1-5 | - |
dc.identifier.issn | 1752-1947 | - |
dc.identifier.uri | http://hdl.handle.net/10722/265954 | - |
dc.description.abstract | Background: Limbic encephalitis is characterized by rapid onset of working memory deficit, mood changes, and often seizures. The condition has a strong paraneoplastic association, but not all cases are invariably due to tumors. Case presentation: We present a case of limbic encephalitis in a Chinese patient who initially presented to our hospital with optic neuritis and no other neurological symptoms. The diagnosis was made radiologically, and cognitive and neurological symptoms did not occur until 5 months later. Extensive investigations for autoimmune, infective, and neoplastic causes were all negative. A working diagnosis of paraneoplastic neurological syndrome was made, and the patient is being managed with high-dose steroid therapy according to the Optic Neuritis Treatment Trial protocol during relapses, as well as with tumor surveillance. Conclusions: This case highlights ocular symptoms as important clues for diagnosing neurological diseases, as well as autoimmune encephalitis as an important differential diagnosis in the management of “idiopathic” optic neuritis in the Chinese population. | - |
dc.language | eng | - |
dc.publisher | BioMed Central Ltd. The Journal's web site is located at http://www.jmedicalcasereports.com/ | - |
dc.relation.ispartof | Journal of Medical Case Reports | - |
dc.rights | Journal of Medical Case Reports. Copyright © BioMed Central Ltd. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Optic neuritis | - |
dc.subject | Limbic encephalitis | - |
dc.subject | Autoimmune encephalitis | - |
dc.subject | Paraneoplastic syndrome | - |
dc.title | Optic neuritis as the initial clinical presentation of limbic encephalitis: a case report | - |
dc.type | Article | - |
dc.identifier.email | Lau, GKK: gkklau@hku.hk | - |
dc.identifier.email | Chan, KH: koonho@hku.hk | - |
dc.identifier.email | Wong, YHI: wongyhi@hku.hk | - |
dc.identifier.email | Lai, JSM: laism@hku.hk | - |
dc.identifier.email | Shih, KC: kcshih@hku.hk | - |
dc.identifier.authority | Lau, GKK=rp01499 | - |
dc.identifier.authority | Chan, KH=rp00537 | - |
dc.identifier.authority | Wong, YHI=rp01467 | - |
dc.identifier.authority | Lai, JSM=rp00295 | - |
dc.identifier.authority | Shih, KC=rp01374 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1186/s13256-018-1893-7 | - |
dc.identifier.pmid | 30509326 | - |
dc.identifier.pmcid | PMC6276199 | - |
dc.identifier.scopus | eid_2-s2.0-85057596090 | - |
dc.identifier.hkuros | 296380 | - |
dc.identifier.volume | 12 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | article no. 357, p. 1 | - |
dc.identifier.epage | article no. 357, p. 5 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1752-1947 | - |