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- Publisher Website: 10.1016/j.semradonc.2006.11.007
- Scopus: eid_2-s2.0-33947502318
- PMID: 17395041
- WOS: WOS:000245612300006
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Article: Physical Models and Simpler Dosimetric Descriptors of Radiation Late Toxicity
Title | Physical Models and Simpler Dosimetric Descriptors of Radiation Late Toxicity |
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Authors | |
Issue Date | 2007 |
Citation | Seminars in Radiation Oncology, 2007, v. 17, n. 2, p. 108-120 How to Cite? |
Abstract | Predicting radiation damage to specific organs is becoming ever more challenging with the use of intensity-modulated beams, nonuniform dose distributions, partial organ irradiation, and interpatient and even intraorgan variations in radiation sensitivity. Data-based physical models can be of use in summarizing complicated dose-volume data to help describe clinical outcomes and ultimately aid in the prediction of clinical toxicity. This article attempts to provide a brief overview of the use of normal tissue complication probability (NTCP) models and other simple dose/volume metrics to describe a few clinically significant complications (either frequent or serious) associated with radiation therapy of the head and neck, thorax, and abdominal-pelvic regions. Specifically, it reviews the application of these methods for late toxicities of the parotid, lung, heart, spinal cord, liver, and rectum. It focuses on organ-specific NTCP parameters as well as simple dosimetric descriptors that might be used to help treatment plan evaluation in clinical practice. © 2007 Elsevier Inc. All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/266871 |
ISSN | 2023 Impact Factor: 2.6 2023 SCImago Journal Rankings: 1.038 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Kong, Feng Ming (Spring) | - |
dc.contributor.author | Pan, Charlie | - |
dc.contributor.author | Eisbruch, Avraham | - |
dc.contributor.author | Haken, Randall K.Ten | - |
dc.date.accessioned | 2019-01-31T07:19:51Z | - |
dc.date.available | 2019-01-31T07:19:51Z | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | Seminars in Radiation Oncology, 2007, v. 17, n. 2, p. 108-120 | - |
dc.identifier.issn | 1053-4296 | - |
dc.identifier.uri | http://hdl.handle.net/10722/266871 | - |
dc.description.abstract | Predicting radiation damage to specific organs is becoming ever more challenging with the use of intensity-modulated beams, nonuniform dose distributions, partial organ irradiation, and interpatient and even intraorgan variations in radiation sensitivity. Data-based physical models can be of use in summarizing complicated dose-volume data to help describe clinical outcomes and ultimately aid in the prediction of clinical toxicity. This article attempts to provide a brief overview of the use of normal tissue complication probability (NTCP) models and other simple dose/volume metrics to describe a few clinically significant complications (either frequent or serious) associated with radiation therapy of the head and neck, thorax, and abdominal-pelvic regions. Specifically, it reviews the application of these methods for late toxicities of the parotid, lung, heart, spinal cord, liver, and rectum. It focuses on organ-specific NTCP parameters as well as simple dosimetric descriptors that might be used to help treatment plan evaluation in clinical practice. © 2007 Elsevier Inc. All rights reserved. | - |
dc.language | eng | - |
dc.relation.ispartof | Seminars in Radiation Oncology | - |
dc.title | Physical Models and Simpler Dosimetric Descriptors of Radiation Late Toxicity | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.semradonc.2006.11.007 | - |
dc.identifier.pmid | 17395041 | - |
dc.identifier.scopus | eid_2-s2.0-33947502318 | - |
dc.identifier.volume | 17 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 108 | - |
dc.identifier.epage | 120 | - |
dc.identifier.isi | WOS:000245612300006 | - |
dc.identifier.issnl | 1053-4296 | - |