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Article: Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA)

TitleAge-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA)
Authors
Keywordsaging
Alpha-synuclein
chaperone-mediated autophagy
knockin mouse model
LRRK2
oligomers
Parkinson disease
protein aggregation
protein degradation
therapeutic strategy
Issue Date2020
PublisherTaylor & Francis: STM, Behavioural Science and Public Health Titles. The Journal's web site is located at http://www.tandfonline.com/loi/kaup20#.VfwhQUaFOnI
Citation
Autophagy, 2020, v. 16 n. 2, p. 347-370 How to Cite?
Persistent Identifierhttp://hdl.handle.net/10722/269578
ISSN
2023 Impact Factor: 14.6
2023 SCImago Journal Rankings: 4.035
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHo, WL-
dc.contributor.authorLeung, CTG-
dc.contributor.authorLiu, H-
dc.contributor.authorPang, SYY-
dc.contributor.authorLam, CSC-
dc.contributor.authorXian, J-
dc.contributor.authorLi, L-
dc.contributor.authorKung, MHW-
dc.contributor.authorRamsden, DB-
dc.contributor.authorHo, SL-
dc.date.accessioned2019-04-24T08:10:32Z-
dc.date.available2019-04-24T08:10:32Z-
dc.date.issued2020-
dc.identifier.citationAutophagy, 2020, v. 16 n. 2, p. 347-370-
dc.identifier.issn1554-8627-
dc.identifier.urihttp://hdl.handle.net/10722/269578-
dc.languageeng-
dc.publisherTaylor & Francis: STM, Behavioural Science and Public Health Titles. The Journal's web site is located at http://www.tandfonline.com/loi/kaup20#.VfwhQUaFOnI-
dc.relation.ispartofAutophagy-
dc.rightsThis is an electronic version of an article published in [include the complete citation information for the final version of the article as published in the print edition of the journal]. [Autophagy] is available online at: http://www.informaworld.com/smpp/ with the open URL of your article.-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectaging-
dc.subjectAlpha-synuclein-
dc.subjectchaperone-mediated autophagy-
dc.subjectknockin mouse model-
dc.subjectLRRK2-
dc.subjectoligomers-
dc.subjectParkinson disease-
dc.subjectprotein aggregation-
dc.subjectprotein degradation-
dc.subjecttherapeutic strategy-
dc.titleAge-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA)-
dc.typeArticle-
dc.identifier.emailHo, WL: hwl2002@hku.hk-
dc.identifier.emailLeung, CTG: gctleung@hku.hk-
dc.identifier.emailLiu, H: liuhf@hku.hk-
dc.identifier.emailPang, SYY: syypang@hku.hk-
dc.identifier.emailXian, J: carmenjw@hku.hk-
dc.identifier.emailLi, L: lilf@hku.hk-
dc.identifier.emailKung, MHW: mhwkung@hkucc.hku.hk-
dc.identifier.emailHo, SL: slho@hku.hk-
dc.identifier.authorityHo, WL=rp00259-
dc.identifier.authorityHo, SL=rp00240-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1080/15548627.2019.1603545-
dc.identifier.scopuseid_2-s2.0-85064493150-
dc.identifier.hkuros297636-
dc.identifier.volume16-
dc.identifier.issue2-
dc.identifier.spage347-
dc.identifier.epage370-
dc.identifier.isiWOS:000466678200001-
dc.publisher.placeUnited States-
dc.identifier.issnl1554-8627-

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