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Article: Application of (4+3) cycloaddition strategies in the synthesis of natural products

TitleApplication of (4+3) cycloaddition strategies in the synthesis of natural products
Authors
Issue Date2018
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cs/index.asp
Citation
Chemical Society Reviews, 2018, v. 47 n. 23, p. 8881-8924 How to Cite?
Abstract(4+3) Cycloadditions have been widely applied in synthesis, and in this review article, we summarize some of the more recent applications, including formal (4+3) cycloadditions, in the synthesis of natural products. Many of these natural product target frameworks have cycloheptane subunits, for which the (4+3) cycloaddition is a convergent strategy for their assembly. Some natural product targets do not possess seven membered rings, and their syntheses have exploited the functional group endowed (4+3) cycloadducts resulting from these reactions, highlighting the utility of this methodology for the synthesis of a range of complex molecules.
Persistent Identifierhttp://hdl.handle.net/10722/272134
ISSN
2023 Impact Factor: 40.4
2023 SCImago Journal Rankings: 12.511
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorYin, Z-
dc.contributor.authorHE, Y-
dc.contributor.authorChiu, P-
dc.date.accessioned2019-07-20T10:36:20Z-
dc.date.available2019-07-20T10:36:20Z-
dc.date.issued2018-
dc.identifier.citationChemical Society Reviews, 2018, v. 47 n. 23, p. 8881-8924-
dc.identifier.issn0306-0012-
dc.identifier.urihttp://hdl.handle.net/10722/272134-
dc.description.abstract(4+3) Cycloadditions have been widely applied in synthesis, and in this review article, we summarize some of the more recent applications, including formal (4+3) cycloadditions, in the synthesis of natural products. Many of these natural product target frameworks have cycloheptane subunits, for which the (4+3) cycloaddition is a convergent strategy for their assembly. Some natural product targets do not possess seven membered rings, and their syntheses have exploited the functional group endowed (4+3) cycloadducts resulting from these reactions, highlighting the utility of this methodology for the synthesis of a range of complex molecules.-
dc.languageeng-
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cs/index.asp-
dc.relation.ispartofChemical Society Reviews-
dc.subject.meshBiological Products-
dc.subject.meshCycloaddition Reaction-
dc.subject.meshCycloheptanes-
dc.subject.meshMolecular Structure-
dc.titleApplication of (4+3) cycloaddition strategies in the synthesis of natural products-
dc.typeArticle-
dc.identifier.emailYin, Z: zsyin@hku.hk-
dc.identifier.emailChiu, P: pchiu@hku.hk-
dc.identifier.authorityChiu, P=rp00680-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1039/C8CS00532J-
dc.identifier.pmid30394457-
dc.identifier.scopuseid_2-s2.0-85057108684-
dc.identifier.hkuros298417-
dc.identifier.volume47-
dc.identifier.issue23-
dc.identifier.spage8881-
dc.identifier.epage8924-
dc.identifier.isiWOS:000451657800013-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl0306-0012-

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